Barrett's Esophagus Clinical Trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 349 clinical trials
Prospective 4D Computed Tomography Angiography Of The Bicuspid Aortic Valve Apparatus: A Comparison Of Bicuspid Aortic Valves With And Without Aortic Insufficiency
The purpose of this study is to characterize the differences in the aortic valve and aortic root anatomy in patients with BAVs in order to better understand the anatomical features that allow the BAV to function normally. With this information, surgeons and cardiologists will be better able to determine which …
Vessel Wall Enhancement in Giant Cell Arteritis
The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes, which may be useful in the diagnosis, prognosis, and treatment of giant cell arteritis (GCA; temporal arteritis). Study participants are eligible if …
2 march edit9
This is a randomized, open-label, parallel group study to determine the optimal dose of CART-19 cells (of the two dose levels being assessed (1-5x10xE8 vs. 1-5x10xE7 CART-19 cells). This trial will be conducted in two stages. In Stage 2, the selected dose cohort will be expanded to enroll additional subjects, …
Effect of Organic Nitrates and Hydralazine on Wave Reflections and Left Ventricular Structure and Function in Heart Failure with Preserved Ejection Fraction
The purpose of this study is to test the effect of prolonged therapy (24 weeks) with isosorbide dinitrate ± hydralazine on arterial wave reflections, exercise capacity, left ventricular (LV) mass/fibrosis and diastolic function in patients with Heart Failure and Preserved Ejection Fraction (HFPEF). This is a double-blind, placebo-controlled pilot randomized …
Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for High Surgical Risk Patients
This is a study of the MitraClip, percutaneous mitral valve repair system in patients with moderate to severe to severe functional mitral regurgitation who need surgical repair but are deemed not appropriate for surgery. Patients will be randomized in a 1:1 fashion to treatment with the Mitra Clip system or …
Preliminary Evaluation of Septin9 in Familial Adenomatous Polyposis Patients
The purpose of this research study is to collect blood samples and applicable medical history from subjects diagnosed with hereditary colon cancer syndromes like FAP, Lynch Syndrome and MYK-associated polyposis and their family members. These samples will be used to evaluate the ability of a blood test to provide early …
Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients with AsYmptomatic Severe Aortic Stenosis
The study is evaluating the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve (THV) in comparison with clinical monitoring in asymptomatic patients over the age of sixty five that have be diagnosed with severe calcific narrowing of the aortic valve (aortic stenosis). Patients will be determined asymptomatic …
A Randomized Double-blind Placebo-controlled Clinical Study to Evaluate Mavacamten (MYK-461) in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy
This is a Phase 3, double-blind, randomized, placebo-controlled, multicenter, international, parallel-group study to evaluate the safety, tolerability, and efficacy of mavacamten compared with placebo (1:1) in participants with symptomatic oHCM. Approximately 220 participants will be enrolled. This includes ~80 participants (~40 per treatment group) who consent to participate in a …
A Pilot Proof of Concept Single-Center Study of the Use of Oritavancin in Systemic Staphylococcus aureus Infections in Patients with Opioid Use Disorder
The study participants will be in the study for approximately 2 months including the screening, intervention phase and the 6 weeks of follow-up time
A Randomized Multicenter Study for Isolated Skin Vasculitis (ARAMIS)
The purpose of this study is to evaluate different treatment options for patients with skin vasculitis (also named cutaneous vasculitis). Patients with isolated cutaneous small vessel vasculitis, medium-sized vessel vasculitis (polyarteritis nodosa), or IgA vasculitis (Henoch-Schönlein purpura) can join this study. The frequently used treatments for skin vasculitis are colchicine, …
