Barrett's Esophagus Clinical Trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 349 clinical trials
Three Approaches to Maintenance Therapy for Chronic Insomnia in Older Adults (R01AG054521)
Medication is FDA approved. The present study is a further evaluation of the behavioral pharmacotherapeutic strategy (i.e., partial reinforcement following the obtention of treatment response with standard treatment) with a particular focus on 1) how low a dose may be used (dose = frequency of active medication) and 2) how …
A single-arm open-label phase 2 study evaluating the efficacy and safety of abemaciclib in patients with recurrent oligodendroglioma
This is a single-center, phase II, single-arm, open label study evaluating the efficacy and safety of abemaciclib for patients with recurrent oligodendroglioma (molecularly defined per the WHO 2016 guidance, i.e., presence of IDH mutation and 1p19q codeletion). The study will enroll 10 subjects who are evaluable for the studys primary …
HOPE in Action Prospective Multicenter Clinical Trial of HIV+ Deceased Donor Kidney Transplants for HIV+ Recipients
Use of an HIV+ deceased donor could increase the risk of death, transplant-related or HIV-related complications; alternatively with effective antiretroviral treatment and careful HIV+ donor selection, these risks may be comparable to kidney transplant using an HIV-negative donor. We hypothesize that receiving a kidney transplant from an HIV+ donor will …
Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET)
Adults 65 and older are more likely to have significant injuries from minor things like falls. They can have problems regaining strength due to sarcopenia (loss of muscle tissue as part of natural aging process). Nicotinamide riboside/pterstilbene (Basis) is commercially available nutraceutical. This randomized, double blind placebo controlled trial will …
Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Sarilumab in Giant Cell Arteritis
The main purpose of this study is to understand how well giant cell arteritis (also known as temporal arteritis; GCA) responds to an investigational drug called sarilumab. Sarilumab needs to be tested to find out if it is safe and effective in treating GCA. An investigational drug is one that …
A Phase II Study of the Anti-GITR Agonist INCAGN01876 and the PD-1 Inhibitor INCMGA00012 in Combination with Stereotactic Radiosurgery in Recurrent Glioblastoma
The following protocol is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and SRS for recurrent GBM. We hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved tumor responses. …
A Novel Method for Glutamate Imaging
This research study will test the performance of new magnetic resonance imaging and spectroscopy techniques at 7.0 Tesla. These new methods have already been tested in model systems and need to be tried on human subjects prior to use in patient populations. The study is expected to continue for five …
CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer
SGM-101 is a fluorochrome-labeled anti-carcino-embryonic antigen (CEA) monoclonal antibody. What this means is that part of SGM-101 is a chemical that is attracted to and will attach to the cells of your cancer. Another part of SGM-101 is a chemical that will glow when infrared light is shined on it. …
Multimodal imaging outcome measures for ALS (Image ALS)
This research study is being done to learn more about changes over time in Positron Emission Tomography/Computed Tomography (PET/CT) imaging in people with amyotrophic lateral sclerosis (ALS). We need data from people with ALS. If you agree to be in this study, you will have up to 6 PET/CT scans …
External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients: A Pilot Trial with Concurrent Controls to Confirm Safety and Assess Preliminary Efficacy
This is an interventional cohort study (n=10) that will involve external drainage of thoracic duct lymph in Surgical ICU patients with septic shock. The lymph drainage will continue for up to a maximum of 7 days and will be continued in those patients discharged from ICU back to the ward …
