Barrett's Esophagus Clinical Trials

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Kidney Disorders: Biological Specimen Repository and Clinical Database

To support the research of kidney disorders by creating a bank of biospecimens and a corresponding database of clinical information that will be used for future, unspecified research. Target population is adults with a kidney disorder, but the study also allows for enrollment of family members, healthy controls, and children.

Artificial Intelligence (AI) Assisted Real-time Adenoma Detection During Colonoscopies

The main hypothesis of this study is that the ADR in the operating room equipped with the GI genius CADe system will be significantly higher than the ADR in the ordinary operating room.

Pilot Study of EsoCheck Compared to Biopsies and Brush Cytology During Endoscopy for Evaluation of Eosinophilic Esophagitis

Another potential promising device is EsoCheck. This is an encapsulated balloon that can be easily swallowed to collect esophageal cells. It is well tolerated and, in Barretts esophagus, detected metaplasia with 91.7% specificity.

A prospective randomized active (warfarin) controlled parallel-arm clinical trial to determine if patients with an On-X aortic valve can be maintained safely and effectively on the factor Xa inhibitor apixaban (PROACT-Xa Trial)

The purpose of this study is to determine if participants with an On-X Prosthetic Heart Valve / On-X aortic valve (a type of mechanical valve) can be maintained safely and effectively on apixaban, an anticoagulant drug different from warfarin.

A Pilot Study of Risk-Guided Cardioprotection with Carvedilol in Breast Cancer Patients Treated with Doxorubicin and/or Trastuzumab

Low risk subjects will be usual care. All subjects will be followed with serial echo, survey, and blood draws.

A Clinical Study Evaluating the data Utility and Usability of Invu on pregnant subjects during virtual survaliance sessions of Fetal and Maternal heart rates and blood pressure readings

Subjects will be given the Invu device to use at home and will be asked to perform at least two, but up to 20 (2x per week for up to 10 weeks) remote monitoring sessions.

Evaluation of in vivo Neuroinflammation in Parkinsons Disease Using 18F-NOS Positron Emission Tomography (PET/CT)

The results of these research tests will not be given to the subject, will not be included in the medical record and will not be used in the subjects clinical management.

Monitoring brain metabolism after glucose intake by MRI methods

Either unlabeled glucose or D2-glucose will be given by oral route in about 250 ml water. MRI will last for 90 minutes. Contrast agents will not be used in this procedure.

Evaluation of Vascular Health Profile in Predicting Venous Thromboembolism

The main goal of this study is to utilize previously validated cytometric markers of to identify cancer patients at high risk of VTE. The primary outcome will be DVT or pulmonary embolism (PE). Patients with pancreatic and brain cancer will be enrolled as these patients are known to have higher …