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Barrett's Esophagus Clinical Trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 349 clinical trials

P Penn Presbyterian Medical Center

An Open-Label Phase 1 Study to Evaluate the Safety of ATA188 in Subjects with Progressive and Relapsing-Remitting Multiple Sclerosis

The purpose of the study is to determine the safety and tolerability of ATA188 in subjects with progressive forms of multiple sclerosis. Up to 42 male or female subjects with progressive forms of MS and 42 subjects with Relapsing-Remitting MS will be enrolled. The subjects will be randomized to receive …

99 years and younger All Phase 1
P Penn Presbyterian Medical Center

Study to Evaluate Imaging Feasibility, Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes Primary Tumors and Tumor Margins in Patients with Solid Tumors

The purpose of this research study is to learn about the safety and effectiveness of using ONM 100 to obtain images of primary tumors and metastatic lymph nodes in patients with solid tumors undergoing routine surgery. Adults at least 18 years of age with a Biopsy-confirmed diagnosis of primary or …

18-99 years All Phase 2
P PETER REESE

A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-Negative kidney recipients

The THINKER-NEXT research study is being done to determine whether it is safe to give a kidney transplant from a donor with hepatitis C to a patient without hepatitis C. The recipient will then be given a drug called Epclusa for 12 weeks to treat hepatitis C. Patients who are …

99 years and younger All Phase 2
E EMILE MOHLER

A Phase II Randomized Double-Blind Multicenter Multinational Placebo-Controlled Parallel-Groups Study to Evaluate the Safety and Efficacy of Intramuscular Injections of Allogeneic PLX-PAD Cells for the Treatment of Subjects with Intermittent Claudication (IC)

In this research study an investigational product called PLX-PAD will be tested to see if it helps claudication. PLX-PAD is made up of mesenchymal-like stromal cells (MSCs), which are similar to stem cells. These cells come from a human placenta (afterbirth) from chosen female donor volunteers. From animal experiments it …

1-99 years All Phase 2
E ELIEZER LEIBU

Trauma Induced Coagulapathy and Inflammation

While a number of factors are known to be associated with the development of trauma induced coagulopathy (TIC), inflammation, and multi-organ failure, we currently cannot predict which patients are at risk for developing these life-threatening conditions with any certainty. In this prospective observational study, we will investigate the many factors …

99 years and younger All
P Penn Presbyterian Medical Center

Targeting the Cholinergic Pathway in HIV-associated Inflammation and Cognitive Dysfunction

Although anti-retroviral therapy (ART) enhances life expectancy and overall quality of life (QoL), HIV-infected individuals are increasingly vulnerable to non-AIDS-related diseases including HIV-associated neurocognitive disorders (HAND). Inflammation is a primary mechanism in the pathogenesis of HAND and tobacco use may further exacerbate inflammation. Conversely, nicotine alone has anti-inflammatory effects suggesting …

40 years and older All Phase N/A
P Penn Presbyterian Medical Center

2D AND 4D CONTRAST-ENHANCED ULTRASOUND EVALUATION OF HEPATOCELLULAR CARCINOMA CHEMOEMBOLIZATION

This is an open-label, non-randomized trial that will be conducted at three clinical sites. The subject population will be patients undergoing transarterial chemoembolization (TACE) for the treatment of hepatocellular carcinoma (HCC) at Thomas Jefferson University, The University of California, San Diego, and University of Pennsylvania. Patients will receive a contrast-enhanced …

99 years and younger All
F FARZANA SAYANI

A Phase 2 Study of PTG-300 in Non-Transfusion Dependent (NTD) and Transfusion-Dependent (TD) Beta-Thalassemia Subjects with Chronic Anemia.

This is a Phase 2 open-label, single-arm design with dose escalation by subject cohort and with the potential for individual titration (dose increase or decrease) within each cohort. Five PTG-300 dose levels/regimens are planned to be tested for each subpopulation of beta-thalassemia (NTD and TD) on separate arms: Cohort 1: …

99 years and younger All Phase 2
L Lizette Grajales

Opioid Taper in Chronic Pain

Are you and your physician planning to taper your opioid dose? If so, you may be eligible to participate in a paid research study looking to evaluate how the perception of pain changes as opioid medication is tapered. To learn more about this study contact research coordinator Lizette at 215-615-0512 or …

21-70 years All Phase N/A
P Penn Presbyterian Medical Center

A Randomized Controled Trial of Transcutaneous Magnetic Stimulation of the Stellate Ganglion to Treat Ventricular Tachycardia Storm

Two arm, randomized controlled trial with sham therapy control arm to assess the efficacy of low-frequency trans-cutaneous magnetic stimulation of the autonomic nerves in the neck for patients with ventricular arrhythmia. Twenty two (22) subjects with a high burden of ventricular arrhythmia will be randomized to undergo 60-minutes of low …

99 years and younger All

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