Barrett's Esophagus Clinical Trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 349 clinical trials
A Phase 1 Open-Label Safety Pharmacokinetic and Preliminary Efficacy Study of STRO-002 An Anti-Folate Receptor alpha Antibody- Drug Conjugate (ADC) In Patients with Advanced Epithelial Ovarian Cancer (including Fallopian Tube or Primary Peritoneal Cancers) and Endometrial Cancers

This includes collection of side effects and measured amounts of STRO-002 in the blood at different time points, known as pharmacokinetics (PK) testing. This dose, the recommended phase 2 dose (RP2D), will be used in Part 2 of this study. Levels (if any) of antibodies in the blood which may …

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  • 19 Feb, 2024
  • 1 location
Sub-study of L-RAD (832203): Collection of Tissue and Fluid Samples for Research in Lymphoproliferative Disorders

., tissue and fluid) obtained solely for the purpose of research. These materials will be used for future, unspecified research.

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  • 19 Feb, 2024
  • 1 location
UPCC 19520: An Open-Label Multi-Institutional Pilot Study to Assess The Use of Glucarpidase in Adult Patients With Osteosarcoma Receiving High-Dose Methotrexate

This study is being done to answer the following question: Does scheduled glucarpidase reduce the levels of methotrexate in patients blood and lead to shorter hospitalizations and a reduction in toxicities? Eligible subjects will be those with osteosarcoma.

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  • 19 Feb, 2024
  • 1 location
An Open Label Study to Assess the Safety and Efficacy of COR-003(2S 4R-Ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

Once the appropriate dose has been determined, subjects will take the study medicine for 6 months. At the end of six months, subjects will be followed for another 6 months so that more information can be collected.

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  • 19 Feb, 2024
  • 1 location
Evaluation of Hyperfine Low Field Portable Point-of-Care Magnetic Resonance Imaging System in Patients with Hydrocephalus

Sometimes such shunts need to be adjusted or replaced if fluid re-accumulates. Medical imaging scans, either computer tomography (CT) or magnetic resonance imaging (MRI), are used to diagnose hydrocephalus in adults and children.

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  • 19 Feb, 2024
  • 1 location
DISSECT-N is an Observational Registry to Assess Real-world Safety and Effectiveness of the Valiant Navion Thoracic Stent Graft in Routine Clinical Practice in Subjects Diagnosed With a Dissection of the Thoracic Aorta

It is an observational registry that introduces no additional testing or procedures to a patient's cardiovascular treatment; all research data will be taken from the subject's standard care information. Adults who intend to be treated with the Valiant Navion graft are eligible for participation, and they will be followed by …

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  • 19 Feb, 2024
  • 1 location
High Velocity Nasal Insufflation (Hi-VNI) Use in Upper Airway Surgery

The goals of this study are to establish the efficacy of Hi-VNI in upper airway surgery from the anesthesiologists' and surgeons' perspectives, and to describe the ideal patient and the ideal pathology as well as suitable clinical scenarios when this oxygenation technique should be selected.

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  • 19 Feb, 2024
  • 1 location
Phase IV Open Label Study of the Effects of Secukinumab on Nail Psoriasis and non-invasive measures of enthesitis

Secukinumab is known as a biologic, and works by blocking the activity of a specific protein in the immune system, interleukin-17A, which is believed to be involved in psoriasis, psoriatic arthritis, and ankylosing spondylitis.Secukinumab will be given at the currently approved dose for psoriasis which is 300 mg subcutaneously (under …

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  • 19 Feb, 2024
  • 1 location
Deep Phenotyping of ANGPTL3 4 and 8 Human Knockouts

Subjects with unusual lipids in subjects with known or suspected genetic variants that may be associated with change in lipoprotein kinetics will have two-night, one-day inpatient stay in CHPS, during which they will undergo extensive evaluation of lipoprotein kinetics using stable isotope techniques, OFTT, and OGTT.

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  • 19 Feb, 2024
  • 1 location
Cycled Phototherapy: A Safer Effective Method to Control

The proposed trial is a minimal-risk safety trial in which extremely premature infants (less than or equal to 750 birth weight and/or less than 27 weeks gestational age) would be randomized to either a continuous phototherapy regimen or to the 15 min cycled phototherapy regimen.

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  • 19 Feb, 2024
  • 1 location