Barrett's Esophagus Clinical Trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 349 clinical trials
A Randomized Placebo-Controlled Study of the Efficacy and Safety of Intracerebral Stem Cells (CTX0E03) in Subjects with Disability Following an Ischemic Stroke

The study drug, including the equipment being used to give the stem cells, is experimental and will be injected into the brain

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  • 19 Feb, 2024
  • 1 location
ALFAPUMP SYSTEM IN THE TREATMENT OF REFRACTORY OR RECURRENT ASCITES: A MULTICENTER SINGLE ARM WITHIN SUBJECT CROSSOVER DESIGN PIVOTAL STUDY

Pivotal cohort patients will undergo a 3-month pre-implant observation phase after enrollment, followed by implantation of the alfapump and 24 months of post-implant follow up. An analysis will be conducted to support an application for device approval when a minimum of 40 treated pivotal cohort patients are through 6 months.

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  • 19 Feb, 2024
  • 1 location
CARDIOVASCULAR PULMONARY AND RENAL PHENOTYPES IN COVID-19 SURVIVORS

The study will specifically focus on the role of the liver, kidneys, lungs, and skeletal muscle, and their interactions with the heart as determinants of cardiovascular disease. This will be achieved by drawing biological specimen from key organs among patients undergoing clinical treatment for COVID-19.

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  • 19 Feb, 2024
  • 1 location
The Role of the Microbiome in Inter-Individual Variability in NSAID Disposition and Response

In Part B indomethacin PK/PD profiles will be analyzed at baseline and following antibiotic treatment to study the effect of the gut microbiome on indomethacin disposition. The proposed studies will lay an important foundation for future investigation of whether alterations in the microbiome might represent a novel mechanism by which …

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  • 19 Feb, 2024
  • 1 location
A Phase 1 Open-Label Multi-Center First in Human Study of TnMUC1-Targeted Genetically-Modified Chimeric Antigen Receptor T Cells in Patients with Advanced TnMUC1-Positive Solid Tumors and Multiple Myeloma

The Phase 1 portion of the trial is designed to identify a dose and regimen of CARTTnMUC1 cells that can be safely administered to patients with refractory malignancies. The single arm Phase 1a expansion portion of the trial includes patients with TnMUC1+ platinum-resistant ovarian cancer.

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  • 19 Feb, 2024
  • 1 location
Trial of Best Available Therapy versus Autologous Hematopoietic Stem Cell Transplant for Treatment-Resistant Relapsing Multiple Sclerosis

Patients who agree to participate in the experimental treatment study will be randomly chosen (like a coin flip) to have an AHSCT or BAT. Neither you nor your doctor are able to decide which treatment you will receive.

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  • 19 Feb, 2024
  • 1 location
Treatment for Mixed Urinary Incontinence: Mid-urethral Sling vs. Botox A

The primary outcome for this trial is the change in severity of MUI symptoms which will be measured at 6 months using the Urogenital Distress Inventory. Secondary objectives include identifying predictors of treatment failure and cost-effectiveness of treatments.

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  • 19 Feb, 2024
  • 1 location
A Phase 2 Dose Ranging Study to Evaluate the Efficacy and Safety of AMG 570 in Subjects with Active Systemic Lupus Erythematosus (SLE) with Inadequate Response to Standard of Care (SOC) Therapy

This is a double-blind, randomized, placebo-controlled, multicenter, phase 2 dose-ranging study to evaluate the efficacy and safety of AMG 570 in subjects with active SLE who are not responding to standard of care. Subjects will be randomized to receive either placebo or 1 of 3 doses of AMG 570 by …

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  • 19 Feb, 2024
  • 1 location
The Cancer of the Pancreas Screening-5

The specific Aims of CAPS5 will be: Aim #1: To evaluate pancreatic fluid mutations and circulating pancreatic epithelial cells as accurate markers of neoplasia by comparing their prevalence in cases with sporadic pancreatic neoplasia to healthy and disease controls.

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  • 19 Feb, 2024
  • 1 location
A pilot study evaluating in vivo PARP-1 expression with18F-FluorThanatrace positron emission tomography (PET/CT) in glioblastoma

Patients may participate in this study if they are at least 22 years of age. Up to 12 subjects will be approached to participate in this companion imaging protocol to undergo brain imaging with the novel radiopharmaceutical [18F]Fluorthanatrace ([18F]FTT) which measure PARP-1 activity using a Positron Emission Tomography (PET/CT) scan.

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  • 19 Feb, 2024
  • 1 location