Neoplasms Clinical Trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 188 clinical trials
METAMORPH
The overarching goal of this study is to identify the genetic and molecular markers of molecular evolution identified in patients who have progressed from a primary diagnosis of breast cancer to recurrent, metastatic disease. As an observational study, this study seeks to gather data regarding the molecular and genetic changes …
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- 19 Feb, 2024
- 1 location
Patient-directed messaging to increase colorectal cancer screening
See attached form
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- 19 Feb, 2024
- 1 location
Evaluating in vivo PARP-1 expression with 18F-FluorThanatrace positron emission tomography (PET/CT) in Pancreatic Cancer
Patients who come to the University of Pennsylvania for diagnosis and/or treatment of pancreatic cancer and who meet the study inclusion criteria may be approached by study personnel for recruitment into this study. Patients will be approached about study participation regardless of race or ethnic background.
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- 19 Feb, 2024
- 1 location
SIMCAP (Surgery in Metastatic Carcinoma of Prostate): Phase 2.5 multi-institution randomized prospective clinical trial evaluating the impact of cytoreductive radical prostatectomy combined with best systemic therapy on oncologic and quality of life outcomes in men with newly diagnosed metastatic prostate cancer
This study investigates the effects of adding cytoreductive radical prostatectomy (CRP) to the standard treatment, best systemic therapy (BST), for metastatic prostate cancer (mPCa). CRP removes as much of the cancer as possible (and radical prostatectomy removes only prostate) while BST uses drugs toxic to cancer cells: chemotherapy and androgen …
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- 19 Feb, 2024
- 1 location
A Randomized Multicenter Phase 2 Study of DSP-7888 Dosing Emulsion in Combination with Bevacizumab versus Bevacizumab Alone in Patients with Recurrent or Progressive Glioblastoma following Initial Therapy
The BBI-DSP-7888-201G trial is designed to compare the overall survival (OS) between treatment with DSP-7888 Dosing Emulsion plus bevacizumab (Bev) versus Bev alone in patients with recurrent or progressive glioblastoma multiforme (GBM) following initial therapy. This is a randomized, active-controlled, multicenter, open-label, parallel groups, Phase 2 study. Approximately 200 patients …
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- 19 Feb, 2024
- 1 location
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- 19 Feb, 2024
- 1 location
Technology for Detection of SARS-Cov-2 in HIV-Positive Cancer Patients
For example, it may be that people who already have other illnesses such as HIV (Human Immunodeficiency Virus), cancer, or other infections may be more likely to get very sick if they also get COVID-19. To check for some such infections, we will take mucus samples from each person’s …
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- 19 Feb, 2024
- 1 location
Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer
The primary tumor must be accessible for vector delivery at the time of standard-of-care staging procedure. The study drug in question is an Investigational New Drug (IND), AdV-tk.
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- 19 Feb, 2024
- 1 location
A Phase 2/3 Randomized Open-Label Study of Toca 511 a Retroviral Replicating Vector Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma
This is a multicenter, randomized, open-label study of Toca 511 and Toca FC versus standard of care (SOC) that comprises Investigators choice of either single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects undergoing resection for first or second recurrence (including this recurrence) of glioblastoma or anaplastic astrocytoma. …
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- 19 Feb, 2024
- 1 location