Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 188 clinical trials
UPCC 09118:A Phase 2 Study of Olaparib Monotherapy in Metastatic Breast Cancer Patients with Germline or Somatic Mutations in DNA Repair Genes (Olaparib Expanded)

This study will evaluate whether olaparib is effective in breast cancer patients whose tumor has a mutation in one of the other genes that function with BRCA1 and BRCA2 to repair damaged DNA.

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  • 19 Feb, 2024
  • 1 location
An Open-Label Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Buccal Soluble Film (DBSF) in Adult Subjects With Epilepsy.

You are being asked to be in this study because you have epilepsy and you take epilepsy medication. Aquestive Therapeutics (the study Sponsor) has begun a research study of an investigational drug called Diazepam Buccal Soluble Film or DBSF as a possible treatment for patients with epilepsy. An investigational drug …

  • 0 views
  • 19 Feb, 2024
  • 1 location
PILOT STUDY EVALUATING THE UPTAKE OF [18F]F-GLN BY PET/CT IN BREAST CANCER

Up to 30 evaluable subjects will participate in a single imaging cohort. Patients will be stratified by breast cancer subtype with prioritization to recruit at least 10 estrogen-receptor-expressing (ER+) and 10 triple-negative breast cancers (TNBC).Patients who come to the University of Pennsylvania for diagnosis and/or treatment of breast cancer and …

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  • 19 Feb, 2024
  • 1 location
A pilot study evaluating in vivo PARP-1 expression with18F-FluorThanatrace positron emission tomography (PET/CT) in glioblastoma

Sub-Investigators in the oncology team will help to identify subjects for the imaging study. Patients may participate in this study if they are at least 22 years of age.

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  • 19 Feb, 2024
  • 1 location
FES PET/CT in Endocrine Refractory Breast Cancer

  Some patients may also undergo a second FES PET/CT scan, at the time of suspected progression of disease to compare for changes in FES uptake measures.   Patients may undergo primary tumor or metastatic biopsy, as part of their clinical care.  Patients may also be enrolled in a separate …

  • 0 views
  • 19 Feb, 2024
  • 2 locations
Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation with Focal Impulse and Rotor Modulation Guided Procedures

An algorithm that has been licensed for use with a novel mapping technology (RhythmView, Abbott Electrophysiology (Topera, Inc.), Menlo Park, CA) for analyzing atrial recordings during human AF, finding that greater than 95% of cases demonstrate either a rapidly spinning rotor (small circuit) or very rapid focal impulse formation.

  • 0 views
  • 19 Feb, 2024
  • 1 location
test cancer API Toggle OFF

See protocol section 2 See protocol section 2 See protocol section 2. this is p tag. header

  • 0 views
  • 10 Mar, 2026
  • 1 location
test cancer API Toggle ON

See protocol section 2 See protocol section 2 See protocol section 2. this is p tag. header

  • 0 views
  • 10 Mar, 2026
  • 1 location
Genetics and Heart Health after Cancer Therapy

We plan to enroll 100 BRCA1/2 mutation carriers who have been treated for breast cancer between 2005 and 2017. They will undergo comprehensive functional cardiovascular phenotyping (including biomarkers, echocardiogram, cardio-pulmonary exercise testing, and surveys) at enrollment and annually for five years.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Evaluation of Vascular Health Profile in Predicting Venous Thromboembolism

The main goal of this study is to utilize previously validated cytometric markers of to identify cancer patients at high risk of VTE. The primary outcome will be DVT or pulmonary embolism (PE). Patients with pancreatic and brain cancer will be enrolled as these patients are known to have higher …

  • 0 views
  • 19 Feb, 2024
  • 1 location