Neoplasms Clinical Trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 187 clinical trials
UPCC 09118:A Phase 2 Study of Olaparib Monotherapy in Metastatic Breast Cancer Patients with Germline or Somatic Mutations in DNA Repair Genes (Olaparib Expanded)
This study will evaluate whether olaparib is effective in breast cancer patients whose tumor has a mutation in one of the other genes that function with BRCA1 and BRCA2 to repair damaged DNA.
An Open-Label Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Buccal Soluble Film (DBSF) in Adult Subjects With Epilepsy.
You are being asked to be in this study because you have epilepsy and you take epilepsy medication. Aquestive Therapeutics (the study Sponsor) has begun a research study of an investigational drug called Diazepam Buccal Soluble Film or DBSF as a possible treatment for patients with epilepsy. An investigational drug …
PILOT STUDY EVALUATING THE UPTAKE OF [18F]F-GLN BY PET/CT IN BREAST CANCER
This is a pilot study in patients with known or suspected primary or metastatic breast cancer with one lesion that is 1.5 cm in diameter or greater may be eligible for this study. Patients may participate in this study if they are at least 18 years of age. Up to …
A pilot study evaluating in vivo PARP-1 expression with18F-FluorThanatrace positron emission tomography (PET/CT) in glioblastoma
This is a companion imaging study that plans to enroll adult subjects with recurrent glioblastoma that meet the eligibility criteria for a treatment trial entitled A phase II study evaluating the efficacy and safety of niraparib and tumor-treating fields in recurrent glioblastoma, IRB 832694/UPCC 03319. IRB 832694 is a study …
FES PET/CT in Endocrine Refractory Breast Cancer
Patients with recurrent or metastatic ER+ breast cancer, who have failed prior endocrine therapy may be eligible for this study. Patients may participate in this study, if they are at least 18 years of age, most participants will be receiving care at the clinical practices of the University of Pennsylvania. …
Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation with Focal Impulse and Rotor Modulation Guided Procedures
An algorithm that has been licensed for use with a novel mapping technology (RhythmView, Abbott Electrophysiology (Topera, Inc.), Menlo Park, CA) for analyzing atrial recordings during human AF, finding that greater than 95% of cases demonstrate either a rapidly spinning rotor (small circuit) or very rapid focal impulse formation. Catheter …
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Genetics and Heart Health after Cancer Therapy
The overall objective of this study is to use patient-centered in vitro and in vivo models to answer the fundamental question of whether or not pathogenic mutations in BRCA1/2 result in an increased risk of CV disease. We plan to enroll 100 BRCA1/2 mutation carriers who have been treated for …
Evaluation of Vascular Health Profile in Predicting Venous Thromboembolism
The main goal of this study is to utilize previously validated cytometric markers of to identify cancer patients at high risk of VTE. The primary outcome will be DVT or pulmonary embolism (PE). Patients with pancreatic and brain cancer will be enrolled as these patients are known to have higher …
