Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 188 clinical trials
Featured trial
A First-in-Human Study of EOS301984 as Monotherapy or Combination Therapy in Adult Participants With Advanced Solid Tumors  

APT-008 is an open-label, Phase I/Ib, dose escalation and expansion cohort study to evaluate the safety, tolerability, Pharmacokinetic (PK), Pharmacodynamic (PD), and preliminary efficacy of EOS301984 as monotherapy and in combination with other anticancer therapies in participants with advanced solid tumors.

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  • 23 Mar, 2026
  • 1 location
Featured trial
Pregabalin (Lyrica) in the Management of Oral Mucositis Pain in Head/Neck Chemoradiation Therapy Patients

Double-blind, randomized, single-center pilot study to assess the effectiveness of pregabalin (Lyrica) in the management of mucositis pain in head and neck cancer.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Featured trial
Normal Donor Human Bone Marrow Donation for Research

We are looking for healthy volunteers to donate bone marrow for research purposes. The Stem Cell & Xenograft Core provides bone marrow to laboratories on Penn’s campus researching leukemia and other blood disorders

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  • 19 Feb, 2024
  • 1 location
Featured trial
IMProving Executive function Study (IMPRES)

Dr. Neill Epperson and her study team at the Penn Center for Women's Behavioral Wellness are seeking women to help understand the effects of a stimulant medication on memory and attention in women who underwent surgically induced menopause.

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  • 19 Feb, 2024
  • 1 location
A PHASE II STUDY EVALUATING THE EFFICACY AND SAFETY OF NIRAPARIB AND TUMOR-TREATING FIELDS IN RECURRENT GLIOBLASTOMA

PARP inhibitors have revolutionized the care of ovarian and breast cancers with BRCA mutations, and, in the case of niraparib, the care of women with ovarian cancer regardless of BRCA status. Based on recent advances in cancer genetics, it is now understood that cellular defects in homologous recombination repair in …

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  • 19 Feb, 2024
  • 1 location
Radiation Oncology Registry

You are being asked to participate in the Radiation Oncology Registry. Participation in this study requires no additional obligations on your part; your participation means you are granting permission for your doctors to extract information from your medical chart and use this data for research purposes.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Study to Evaluate Imaging Feasibility, Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes Primary Tumors and Tumor Margins in Patients with Solid Tumors

Patients will be recruited if they have the following diagnoses: Part 1: Biopsy-confirmed diagnosis of Stage 0 to 4 HNSCC or primary breast cancer. Part 2: Biopsy-confirmed diagnosis of Stage 2 to 4 or higher HNSCC, breast cancer, colorectal cancer, prostate cancer, bladder cancer, ovarian cancer The study intervention is …

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  • 19 Feb, 2024
  • 1 location
A Phase 1 Open-Label Safety Pharmacokinetic and Preliminary Efficacy Study of STRO-002 An Anti-Folate Receptor alpha Antibody- Drug Conjugate (ADC) In Patients with Advanced Epithelial Ovarian Cancer (including Fallopian Tube or Primary Peritoneal Cancers) and Endometrial Cancers

The purpose of Part 2 is to determine: What effects, good and/or bad, STRO-002 has on subjects including ADA as defined above How their cancer responds to treatment with STRO-002 The amount of STRO-002 in the blood at different times (PK) Key Eligibility

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  • 19 Feb, 2024
  • 1 location
CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer

The purposes of this study are to test the effectiveness of the study drug, SGM-101 to allow the doctor who will perform the surgery to remove your cancer to see better which tissue is cancer and which is healthy so that the surgery can be performed more precisely to get …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers

The purpose of this study is to find if adding the study drug, nivolumab (also known as OPVIDO), will limit lung cancer from growing back in patients with early stage non-small cell lung cancer. Nivolumab is a drug that may turn on the body's immune system to attack any cancer …

  • 0 views
  • 19 Feb, 2024
  • 1 location