Barrett's Esophagus Clinical Trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 349 clinical trials
Randomized Study of Cranial Blocks for Postoperative Anesthesia to Reduce Pain and Postoperative Opioid Usage

The research study is being conducted to look at the effectiveness of analgesia (pain medication) by scalp nerve block with various medications that will help doctors to more effectively control pain after surgery and for a longer period of time. 

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  • 19 Feb, 2024
  • 1 location
Exploratory Study of Mavacamten (MYK-461) in Patients with Symptomatic Non-obstructive Hypertrophic Cardiomyopathy (nHCM) and Preserved Left Ventricular Ejection Fraction

The purpose of this study is to compare the effect of the investigational drug, mavacamten, (MYK-461), to a placebo (an inactive substance) in patients with Non-obstructive Hypertrophic Cardiomyopathy (nHCM).

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  • 19 Feb, 2024
  • 1 location
Pilot study for functional and structural MR Imaging of Endobroncial valve recipients using hyperpoloarized XENON-129

We propose to use gas Magnetic Resonance Imaging (MRI) using the inhaled contrast agent, hyperpolarized (HP) xenon-129, to study the lungs of 20 volunteers who have received or will receive endobronchial valve (EBV) therapy as a treatment for COPD. Since its recent FDA approval, investigators have yet to explicitly assess …

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  • 19 Feb, 2024
  • 1 location
Optimization of Clinical Trial Design in Cutaneous Lupus

Patients with CLE who are 18 years old and over and with demonstrable lesions will be recruited. Subjects' medical history, current therapies/medications, results of patient and physician questionnaires and other information obtained from subjects' medical records will be evaluated.

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  • 19 Feb, 2024
  • 1 location
A Phase 1 Randomized Placebo-Controlled Blinded Multiple Ascending Dose Study to Evaluate VIB7734 in Systemic Lupus Erythematosus Cutaneous Lupus Erythematosus Sjogrens Syndrome Systemic Sclerosis Polymyositis and Dermatomyositis

Cohort 1 has been completed. 24 subjects are needed for Cohorts 2 and 3. Safety and tolerability will be reviewed before starting the next cohort. Three doses VIB7734 will be given SC in ascending doses per cohort every 4 weeks. Key eligibility criteria: Subjects must be 18 to 75 years …

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  • 19 Feb, 2024
  • 1 location
Augmentation versus Switch: Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders with Treatment Resistant Depression (ASCERTAIN-TRD)

Adequate ADT is defined as a therapeutically sufficient dose for a sufficient treatment period, which would be expected to be effective as listed in the MGH Antidepressant Treatment Response Questionnaire (ATRQ). Patients will be randomized in a 1:1:1 fashion to one of three open-label treatment arms: a) aripiprazole augmentation, b) …

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  • 19 Feb, 2024
  • 1 location
A Phase 3 Multicenter Randomized Double-blind Placebo-controlled Trial to Evaluate the Efficacy Safety and Tolerability of Brexpiprazole as Adjunctive Therapy in the Maintenance Treatment of Adults With Major Depressive Disorder

This trial is a phase 3, double-blind, placebo-controlled, randomized withdrawal maintenance trial of brexpiprazole in subjects who require adjunctive treatment of MDD designed to fulfill a post-marketing commitment to the US Food and Drug Administration (FDA). There is a paucity of data on long-term use of the combination of ADT …

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  • 19 Feb, 2024
  • 1 location
Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

A punch skin biopsy at a site of active vasculitis will be the source of material for histopathologic and transcriptomic evaluation. The histopathology of cutaneous vasculitis will be characterized using a standardized, systematic approach.

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  • 19 Feb, 2024
  • 1 location
Biofabrication of Vaginal support Using Vaginally Derilved Cells: a Feasibillity Study

This study will determine the feasibility of using cells obtained from samples of vaginal tissue to bio-fabricate uterosacral ligaments (bioUSLs.) These bioUSLs will be tested for strength and those of women of different age groups will be compared. Additionally bioUSL between women with pelvic organ prolapse (POP) and those without …

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  • 19 Feb, 2024
  • 1 location