Lymphocytic Leukemia, Acute Clinical Trials

A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 79 clinical trials
(PREDICT) A Multi-Center Study in Patients Undergoing Anthracycline-Based Chemotherapy to Assess the Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment

Additionally, cardiac disease remains one of the most common illness affecting all patients, including those with cancer. As a result, there is a mandate from the Institute of Medicine to improve the recognition and treatment of side effects for cancer survivors [2].

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  • 19 Feb, 2024
  • 1 location
The Effect of Potassium Nitrate [KNO3] on Exercise Capacity in Heart Failure Patients.

This study will test whether Potassium Nitrate (KNO3) will improve how people with HFpEF [Diastolic Heart Failure] can exercise. In HFpEF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to becoming tired and short …

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  • 19 Feb, 2024
  • 1 location
METAMORPH

This is a cohort study of women with suspected or confirmed recurrent breast cancer, with accessible tumor by standard clinical biopsy, prior to starting a new therapy for recurrent metastatic disease. Study participants will be ascertained from the population of all persons greater than eighteen years of age receiving care …

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  • 19 Feb, 2024
  • 1 location
“Real World” Administration of Zepatier (Grazoprevir plus Elbasvir in Chronic Hemodialysis Patients with Hepatitis C Infection. Strategies for Identification of Candidate Hemodialysis Patients, Obtainment of Insurance Approval, Treatment Guidelines, and Laboratory and Clinical Monitoring During Therapy Directed to Nephrologists

If you need 16 weeks of treatment or the addition of Ribavirin you will be told at the screening visit. Routine testing of all the patients in your dialysis unit, has identified patients such as yourself, with blood studies that demonstrate a hepatitis C infection.

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  • 19 Feb, 2024
CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer

The purposes of this study are to test the effectiveness of the study drug, SGM-101 to allow the doctor who will perform the surgery to remove your cancer to see better which tissue is cancer and which is healthy so that the surgery can be performed more precisely to get …

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  • 19 Feb, 2024
  • 1 location
Cardiovascular function in leukemia patients: an observational prospective study

Adults with recently diagnosed acute leukemia at the hospital of University of Pennsylvania or the outpatient Perleman Center for Advanced Medicine will be selected. All patients will be studied using echocardiograms and blood tests before chemotherapy, 14 days, 28 days, 45-60 days, 6 months, and 12 months after the first …

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  • 19 Feb, 2024
  • 1 location
A Phase 2/3 Randomized Open-Label Study of Toca 511 a Retroviral Replicating Vector Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma

Stratification will be done by IDH mutation (present or absent), by Karnofsky performance status (KPS [70-80 vs 90-100]) and by geographical region. All subjects will have a Gd-MRI scan 24 to 48 hours after the resection for recurrent disease and a baseline scan prior to initiating Toca FC, chemotherapy, or …

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  • 19 Feb, 2024
  • 1 location
A Phase 2 Multi-center Randomized Double-Blind Placebo-Controlled Dose Range Finding Study to Evaluate the Safety Hemodynamic Effects and Efficacy of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects who have Diabetic Foot Ulcer with Peripheral Arterial Disease

During the Follow-up Period, subjects will be evaluated at Months 3, 4, 5, 6 and 12. All subjects are to receive standard treatment for DFU while receiving IP or placebo and throughout the study. An external data monitoring committee (DMC) will be convened to review interim efficacy and safety data …

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  • 19 Feb, 2024
  • 1 location
Targeting the Cholinergic Pathway in HIV-associated Inflammation and Cognitive Dysfunction

In this double-blind, placebo-controlled crossover study, HIV-infected individuals (N=120; 60 smokers, 60 nonsmokers) will be randomized to 12 weeks of GAL or placebo, followed by a 4-week washout, then 12 weeks of GAL or placebo (arms switched). All subjects will be stable on ART and the GAL dose will follow …

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  • 19 Feb, 2024
  • 1 location
Suicide and Trauma in Persons living with HIV

We will repeat these analyses with the larger electronic medical record system using a de-identified database of all HIV+ individuals, generated in collaboration with the Clinical Research Computing Unit (CRCU) at Penn. In Phase II, we will follow a small sample (n = 10-20) of participants who have HIV for …

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  • 19 Feb, 2024
  • 1 location