Lymphocytic Leukemia, Acute Clinical Trials

A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 79 clinical trials
Psoriasis Specimen BioBank

We propose creating a biobank of specimens from patients with psoriatic disease (psoriasis and/or psoriatic arthritis).We propose prospectively collecting specimens from 200 patients with psoriatic disease, 18 years of age and older, able to provide consent, seen at PENN and deeply phenotyped clinically. All prospective participants will have had to …

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  • 19 Feb, 2024
  • 1 location
DISSECT-N is an Observational Registry to Assess Real-world Safety and Effectiveness of the Valiant Navion Thoracic Stent Graft in Routine Clinical Practice in Subjects Diagnosed With a Dissection of the Thoracic Aorta

It is an observational registry that introduces no additional testing or procedures to a patient's cardiovascular treatment; all research data will be taken from the subject's standard care information. Adults who intend to be treated with the Valiant Navion graft are eligible for participation, and they will be followed by …

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  • 19 Feb, 2024
  • 1 location
Trial to Optimize Patients Selection for Endovascular Treatment in Acute Ischemic Stroke

Use of devices to remove the clot (mechanical thrombectomy) has been shown to improve outcomes in patients with a clot in one of the large arteries of the brain. However, not all patients with a clot in one of the large arteries are treated with these devices. To select the …

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  • 19 Feb, 2024
  • 1 location
Substudy: Understanding COVID-19 vaccine responses in the setting of immunotherapy

Since its emergence, SARS-Cov2 has rapidly and widely spread across the globe due to lack of prior protective immunity in the human species. With widespread mitigation measures, all efforts focused on generating effective vaccination strategies that will provide herd immunity and protect the most vulnerable populations.

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  • 19 Feb, 2024
  • 1 location
A Randomized Placebo-Controlled Study of the Efficacy and Safety of Intracerebral Stem Cells (CTX0E03) in Subjects with Disability Following an Ischemic Stroke

The research study is being conducted to find out if this study drug provides any improvement in the arm and/or leg function affected by the stroke. The study will also gather more information about the safety of the study drug, surgical procedure and equipment used to inject the study drug. …

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  • 19 Feb, 2024
  • 1 location
UPCC 04717: Phase I open label dose-escalation study to evaluate the safety expansion persistence of a single dose of UCART19 (allogeneic engineered T-cells expressing anti-CD19 chimeric antigen receptor) administered intravenously in patients with relapsed or refractory CD19 positive B-cell acute lymphoblastic leukaemia (B-ALL)

The main aims of this study are to test the safety of up to 4 different doses of UCART19, and to identify the best dose of UCART19, by measuring what has happened to the leukemia cells at day 28 (28 days after the administration of UCART19), day 84 (84 days …

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  • 19 Feb, 2024
  • 1 location
Phase 1 Study of Autologous Anti-CD22 Chimeric Antigen Receptor Redirected T Cells (CART22-65s) alone and when co-administered with humanized Anti-CD19 Chimeric Antigen Receptor Redirected T cells (huCART19) In Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia

This is a single center, single arm, open-label Phase 1 study with two cohorts to determine the safety and feasibility of infusing CART22-65s with or without huCART19 after administration of lymphodepleting chemotherapy in adult patients with relapsed or refractory B-ALL.

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  • 19 Feb, 2024
  • 1 location
Serenity for All

You are invited to participate in this online research survey, Serenity for All. We are aiming to get 100 people to complete this survey.

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  • 19 Feb, 2024
  • 1 location
A Better FIT! Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment

A 28-week research study is being conducted that is designed to help all participants lose weight. All participants will receive lifestyle modification (diet, exercise, and behavioral treatment). Participants who do not lose weight with lifestyle modification alone also will be prescribed an FDA-approved weight loss medication (phentermine) or placebo.

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  • 21 Nov, 2025
  • 1 location
Novel neural circuit biomarkers of major depression response to computer-augmented CBT (1R01MH110939 - 01A1)

MDD subjects will be scheduled to receive CCBT at the first available appointment; all will be scheduled within 4 weeks. All subjects will have an fMRI at baseline; MDD subjects will have an fMRI after treatment. MDD subjects scheduled to start CCBT treatment after 3 weeks will complete an additional …

  • 0 views
  • 19 Feb, 2024
  • 1 location