Lymphocytic Leukemia, Acute Clinical Trials

A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 79 clinical trials
Effect of Organic Nitrates and Hydralazine on Wave Reflections and Left Ventricular Structure and Function in Heart Failure with Preserved Ejection Fraction

This is a double-blind, placebo-controlled pilot randomized study in which the effects of placebo and 2 vasoactive interventions (isosorbide dinitrate or isosorbide dinitrate + hydralazine) administered for 24 weeks will be assessed in patients with HFPEF. A total of 42 patients with HFPEF will be enrolled across all sites over …

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  • 19 Feb, 2024
  • 1 location
Psoriasis Specimen BioBank

We propose creating a biobank of specimens from patients with psoriatic disease (psoriasis and/or psoriatic arthritis).We propose prospectively collecting specimens from 200 patients with psoriatic disease, 18 years of age and older, able to provide consent, seen at PENN and deeply phenotyped clinically. All prospective participants will have had to …

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  • 19 Feb, 2024
  • 1 location
Transcranial Magnetic Stimulation Exploration of Motor Cortex Functional Anatomy

The purpose of the proposed study is to explore the nature of the codes that are present in the primary motor cortex. All complex actions involves the contraction of multiple muscles, the timing and intensity of which is precisely modulated. The traditional view of this process is that an abstract …

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  • 19 Feb, 2024
  • 1 location
(PREDICT) A Multi-Center Study in Patients Undergoing Anthracycline-Based Chemotherapy to Assess the Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment

Additionally, cardiac disease remains one of the most common illness affecting all patients, including those with cancer. As a result, there is a mandate from the Institute of Medicine to improve the recognition and treatment of side effects for cancer survivors [2].

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  • 19 Feb, 2024
  • 1 location
The Effect of Potassium Nitrate [KNO3] on Exercise Capacity in Heart Failure Patients.

This study will test whether Potassium Nitrate (KNO3) will improve how people with HFpEF [Diastolic Heart Failure] can exercise. In HFpEF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to becoming tired and short …

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  • 19 Feb, 2024
  • 1 location
METAMORPH

This is a cohort study of women with suspected or confirmed recurrent breast cancer, with accessible tumor by standard clinical biopsy, prior to starting a new therapy for recurrent metastatic disease. Study participants will be ascertained from the population of all persons greater than eighteen years of age receiving care …

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  • 19 Feb, 2024
  • 1 location
CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer

The purposes of this study are to test the effectiveness of the study drug, SGM-101 to allow the doctor who will perform the surgery to remove your cancer to see better which tissue is cancer and which is healthy so that the surgery can be performed more precisely to get …

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  • 19 Feb, 2024
  • 1 location
DISSECT-N is an Observational Registry to Assess Real-world Safety and Effectiveness of the Valiant Navion Thoracic Stent Graft in Routine Clinical Practice in Subjects Diagnosed With a Dissection of the Thoracic Aorta

It is an observational registry that introduces no additional testing or procedures to a patient's cardiovascular treatment; all research data will be taken from the subject's standard care information. Adults who intend to be treated with the Valiant Navion graft are eligible for participation, and they will be followed by …

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  • 19 Feb, 2024
  • 1 location
A Phase 2/3 Randomized Open-Label Study of Toca 511 a Retroviral Replicating Vector Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma

Stratification will be done by IDH mutation (present or absent), by Karnofsky performance status (KPS [70-80 vs 90-100]) and by geographical region. All subjects will have a Gd-MRI scan 24 to 48 hours after the resection for recurrent disease and a baseline scan prior to initiating Toca FC, chemotherapy, or …

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  • 19 Feb, 2024
  • 1 location
A Phase 2 Multi-center Randomized Double-Blind Placebo-Controlled Dose Range Finding Study to Evaluate the Safety Hemodynamic Effects and Efficacy of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects who have Diabetic Foot Ulcer with Peripheral Arterial Disease

During the Follow-up Period, subjects will be evaluated at Months 3, 4, 5, 6 and 12. All subjects are to receive standard treatment for DFU while receiving IP or placebo and throughout the study. An external data monitoring committee (DMC) will be convened to review interim efficacy and safety data …

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  • 19 Feb, 2024
  • 1 location