Surgery Clinical Trials

CAROTID REVASCULARIZATION AND MEDICAL MANAGEMENT FOR ASYMPTOMATIC CAROTID STENOSIS TRIAL (CREST-2) PROTOCOL  

CREST-2 is a national multicenter stroke prevention study that is actively enrolling participants with narrowing in their carotid artery WITHOUT stroke or stroke warning signs (TIAs or mini-strokes). This study is comparing intensive medical management alone to intensive medical management used in combination with a procedure to remove plaque buildup …

A Phase 2 Multicenter, Double-blind, Randomized, Placebo-Controlled Trial to Evaluate Oral Ifetroban in Subjects with Symptomatic Aspirin Exacerbated Respiratory Disease (AERD)

The primary purpose of this study is to determine the therapeutic effectiveness of Ifetroban to improve sinus and nasal symptoms and quality of life in subjects with Aspirin Exacerbated Respiratory Disease (AERD).

Inspire Upper Airway Stimulation System for Obstructive Sleep Apnea: Post Approval Study

Patients with Obstructive Sleep Apnea (OSA) who are interested in pursuing surgical treatment may be candidates for the Inspire device, an FDA-approved upper airway stimulation device that can help to treat OSA. This trial is collecting long-term safety and efficacy data in participants that are implanted with the Inspire device.

A Six-Week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Subjects with Obstructive Sleep Apnea (OSA)

Medication trial for the treatment of excessive sleepiness in adult subjects with treated or untreated obstructive sleep apnea (OSA).

Penn Uterine Transplantation for Uterine Factor Infertility (UNTIL) Trial

The UNTIL Trial is a new clinical research trial that offers uterine transplantation to women with uterine factor infertility (UFI). Participation in this trial requires going through an extensive selection process, creation of embryos through in vitro fertilization, and multiple surgeries. Study participants may remain in the study for 5-10 …

Randomized Controlled Trial to Evaluate the Effect of Lost Wage Reimbursement to Potential Kidney Donors on Living Donation Rates

This study is being done to learn if offering to reimburse kidney donors for wages they would lose by being off work during the donation evaluation and surgery process increases the likelihood of the kidney transplant recipient to receive a living kidney transplant within one year. Eligible subjects will be …

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