Surgery Clinical Trials
A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 288 clinical trials
CAROTID REVASCULARIZATION AND MEDICAL MANAGEMENT FOR ASYMPTOMATIC CAROTID STENOSIS TRIAL (CREST-2) PROTOCOL
CREST-2 is a national multicenter stroke prevention study that is actively enrolling participants with narrowing in their carotid artery WITHOUT stroke or stroke warning signs (TIAs or mini-strokes). This study is comparing intensive medical management alone to intensive medical management used in combination with a procedure to remove plaque buildup …
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- 21 Nov, 2025
- 1 location
A Phase 2 Multicenter, Double-blind, Randomized, Placebo-Controlled Trial to Evaluate Oral Ifetroban in Subjects with Symptomatic Aspirin Exacerbated Respiratory Disease (AERD)
The primary purpose of this study is to determine the therapeutic effectiveness of Ifetroban to improve sinus and nasal symptoms and quality of life in subjects with Aspirin Exacerbated Respiratory Disease (AERD).
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- 19 Feb, 2024
- 1 location
Inspire Upper Airway Stimulation System for Obstructive Sleep Apnea: Post Approval Study
Patients with Obstructive Sleep Apnea (OSA) who are interested in pursuing surgical treatment may be candidates for the Inspire device, an FDA-approved upper airway stimulation device that can help to treat OSA. This trial is collecting long-term safety and efficacy data in participants that are implanted with the Inspire device.
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- 19 Feb, 2024
- 1 location
A Six-Week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Subjects with Obstructive Sleep Apnea (OSA)
Medication trial for the treatment of excessive sleepiness in adult subjects with treated or untreated obstructive sleep apnea (OSA).
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- 19 Feb, 2024
- 1 location
Penn Uterine Transplantation for Uterine Factor Infertility (UNTIL) Trial
The UNTIL Trial is a new clinical research trial that offers uterine transplantation to women with uterine factor infertility (UFI). Participation in this trial requires going through an extensive selection process, creation of embryos through in vitro fertilization, and multiple surgeries. Study participants may remain in the study for 5-10 …
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- 19 Feb, 2024
- 1 location
High Velocity Nasal Insufflation (Hi-VNI) Use in Upper Airway Surgery
The goals of this study are to establish the efficacy of Hi-VNI in upper airway surgery from the anesthesiologists' and surgeons' perspectives, and to describe the ideal patient and the ideal pathology as well as suitable clinical scenarios when this oxygenation technique should be selected.
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- 19 Feb, 2024
- 1 location
CYTOSORB REDUCTION OF FREE HEMOGLOBIN/ACUTE KIDNEY INJURY (AKI) DURING CARDIAC SURGERY - REFRESH II
Reliance Agreement Request - Please refer to WIRB
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- 19 Feb, 2024
- 1 location
UPCC 07518: Pembrolizumab in combination with chemotherapy and image-guided surgery for malignant pleural mesothelioma (MPM).
The study is a single-arm phase I trial to evaluate the safety, feasibility, and preliminary efficacy of the addition of pembrolizumab and image-guided resection to surgical therapy and chemotherapy for MPM
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- 19 Feb, 2024
- 1 location
CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer
The purposes of this study are to test the effectiveness of the study drug, SGM-101 to allow the doctor who will perform the surgery to remove your cancer to see better which tissue is cancer and which is healthy so that the surgery can be performed more precisely to get …
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- 19 Feb, 2024
- 1 location
Study to Evaluate Imaging Feasibility, Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes Primary Tumors and Tumor Margins in Patients with Solid Tumors
The main purpose of this study is to investigate whether ONM-100 can be used to image primary tumors and metastatic lymph nodes at time points earlier than 24 ±8 hours in patients undergoing routine surgery of their solid cancers and whether the diagnostic performance to detect metastatic lymph nodes can …
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- 19 Feb, 2024
- 1 location