Surgery Clinical Trials
A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 288 clinical trials
Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
Nivolumab is a drug that may turn on the body's immune system to attack any cancer cells that may remain after surgery.
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- 19 Feb, 2024
- 1 location
Preoperative use of radiation boost to enhance effectiveness of immune checkpoint blockade therapy in operable breast cancer
We will employ a Simon Two Stage design to evaluate the safety, feasibility, and efficacy of combination radiation boost and a single pembrolizumab infusion prior to definitive surgery.
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- 19 Feb, 2024
- 1 location
Evaluation of Corneal Confocal Microscopy in Ocular Surface Disease and/or Neuropathic Pain Patients
Patients excluded from this study will be those who are members of the vulnerable population or have any physical or mental condition that would interfere with the study. Also, patients who have had intraocular surgery or ocular laser surgery within 2 months before enrollment, or have a history of ocular …
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- 19 Feb, 2024
- 1 location
Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for High Surgical Risk Patients
This is a study of the MitraClip, percutaneous mitral valve repair system in patients with moderate to severe to severe functional mitral regurgitation who need surgical repair but are deemed not appropriate for surgery. Patients will be randomized in a 1:1 fashion to treatment with the Mitra Clip system or …
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- 19 Feb, 2024
- 1 location
Legionella Pneumonia's Effect on Olfactory Function
The goal of this study is to determine whether those who have had Legionnaires' disease suffer smell loss.
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- 19 Feb, 2024
- 1 location
Preliminary Evaluation of Septin9 in Familial Adenomatous Polyposis Patients
If colectomy is performed, blood draws will occur 7 days(+/- 3days) before and 28 days (+/-7 days) after surgery.
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- 19 Feb, 2024
- 1 location
DISSECT-N is an Observational Registry to Assess Real-world Safety and Effectiveness of the Valiant Navion Thoracic Stent Graft in Routine Clinical Practice in Subjects Diagnosed With a Dissection of the Thoracic Aorta
A "Type B" aortic dissection occurs specifically in the descending thoracic aorta. Repair of the dissection via open surgery has historically yielded poor results, and the standard treatment is now thoracic endovascular aneurysm repair (TEVAR). In these minimally invasive procedures, a stent graft is inserted into the aorta via an …
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- 19 Feb, 2024
- 1 location
A Phase 2/3 Randomized Open-Label Study of Toca 511 a Retroviral Replicating Vector Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma
This is a multicenter, randomized, open-label study of Toca 511 and Toca FC versus standard of care (SOC) that comprises Investigators choice of either single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects undergoing resection for first or second recurrence (including this recurrence) of glioblastoma or anaplastic astrocytoma. …
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- 19 Feb, 2024
- 1 location
Treatment for Mixed Urinary Incontinence: Mid-urethral Sling vs. Botox A
The primary objective is to estimate the effect of 100 units of intradetrusor injections of Botulinum toxin A (Botox A ®) compared to mid-urethral sling surgery for the treatment of MUI in 110 women. Participants in the Botox A arm may receive one additional injection of 100 units Botox A …
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- 19 Feb, 2024
- 1 location
Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination with REGN2810 in Subjects with Newly-Diagnosed Glioblastoma (GBM)
By blocking PD-1, cemiplimab may help your immune system to attack the cancer. The usual way to treat GBM is to have surgery to remove the tumor followed by radiation therapy. Some patients may also receive a chemotherapy pill called temozolomide.
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- 19 Feb, 2024
- 1 location