Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 288 clinical trials
A Randomized Placebo Surgery Controlled Double-blinded Multi-center Phase 2 Clinical Trial Evaluating Efcacy and Safety of VY-AADC02 in Advanced Parkinsons Disease with Motor Fluctuations

It is necessary to evaluate the benet of a new, experimental treatment by having a similar group for comparison (placebo). PD studies in the past have used a placebo surgery for this reason.Other than the surgical team, neither you nor the rest of the study team will know if you …

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  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Safety and Efficacy of Image Guided Surgery using Indocyanine Green for Intramolecular Imaging of Solid Tumors Compared to Standard of Care (TumorGlow) (PRIME)

Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove primary tumor nodules in a satisfactory manner as well as lingering metastases in sentinel lymph nodes.

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  • 19 Feb, 2024
  • 1 location
SIMCAP (Surgery in Metastatic Carcinoma of Prostate): Phase 2.5 multi-institution randomized prospective clinical trial evaluating the impact of cytoreductive radical prostatectomy combined with best systemic therapy on oncologic and quality of life outcomes in men with newly diagnosed metastatic prostate cancer

The target population are men at least 18 years old, with newly diagnosed mPCa, havent received surgery, chemotherapy, or radiotherapy, have been on ADT for no more than six months. Randomization will be into (1/2); Arm 1: subjects receive BST, Arm 2: subjects receive ADT for at least one month …

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  • 19 Feb, 2024
  • 1 location
Surgical Therapy for Obstructive Sleep Apnea on Blood Pressure & Peripheral Arterial Tonometry

The research study is being done to look at the effect of sleep apnea surgery on different measures ofcardiovascular (heart) function in people with obstructive sleep apnea.

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  • 19 Feb, 2024
  • 1 location
A Phase III multi-center double-blind randomized withdrawal study of LCI699 following a 24 week single-arm open-label dose titration and treatment period to evaluate the safety and efficacy of LCI699 for the treatment of patients with Cushings disease (PRIME)

The study aims to confirm the long-term efficacy and safety of LCI699 for the treatment of patients with Cushing's disease who have had had surgery that has not been successful, or are not a good surgical candidate, or refuse surgery, and have not received radiation treatment for this condition within …

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  • 19 Feb, 2024
  • 1 location
Towards predicting the analgesic response to ibuprofen following third-molar extraction

The purpose of this study is to see if there are substances in your blood and urine which we will take both before and after your wisdom teeth surgery that can tell us how you personally will respond to ibuprofen in comparison to placebo (an inactive sugar pill). We will …

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  • 19 Feb, 2024
  • 1 location
A Prospective Observational Study of Outcomes from Proximal Thoracic Aortic Disease

The purpose of this registry is to collect real-time data for those patients who have aortic disease of their ascending (top) aorta and the aortic arch (curved area where the vessels that supply the brain with blood). The current treatment requires open surgery or a hybrid procedure (open surgery with …

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  • 19 Feb, 2024
  • 1 location
Prospective Clinical Study of Tri-planar TarsometatarsL (TMT) ArthrodesIs with Early Weight-Bearing after Lapiplasty Procedure

The study will also determine if putting weight on your foot shortly after surgery affects how well your bone heals (fuse) after the Lapiplasty procedure. Information about pain caused by the bunion and how whether your pain improves and your satisfaction with the procedure will also be collected throughout the …

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  • 19 Feb, 2024
  • 1 location
To Serenade or To Sedate? That is Still The Question - A Followup Trial On Anxiolytic Options Before Peripheral Nerve Blocks

The patient's participation will last for approximately 30-60 minutes from the time you agree in taking part of the study to after the procedure is done. Before and after the surgery, we will conduct an anxiety scoring test which includes six questions to answer and takes only a few minutes.

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  • 19 Feb, 2024
  • 1 location
Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer

Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have recurrence. Additional immunotherapeutic agents given before surgery may be greatly reduce recurrence.

  • 0 views
  • 19 Feb, 2024
  • 1 location