Birth Defects Clinical Trials
A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 17 clinical trials
Penn Uterine Transplantation for Uterine Factor Infertility (UNTIL) Trial
The UNTIL Trial is a new clinical research trial that offers uterine transplantation to women with uterine factor infertility (UFI). Participation in this trial requires going through an extensive selection process, creation of embryos through in vitro fertilization, and multiple surgeries. Study participants may remain in the study for 5-10 …
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- 19 Feb, 2024
- 1 location
Promoting Recovery Optimization with WALKing Exercise after Stroke (PROWALKS)
The goal of this study is to improve walking ability after stroke. The interventions in this study will test whether combining fast walking training with a step activity monitoring program (FAST+SAM) is better in improving real-world walking activity compared to fast walking training alone (FAST) or a step activity monitoring …
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- 19 Feb, 2024
- 1 location
Development of a reliable means for functional assessment of liver performance after Fontan operation: dual cholate clearance assay
In these populations, the assay may be able to predict more subtle or sub-clinical liver abnormalities that blood tests cannot detect. HepQuant® is a test that examines the ability of the liver to process a substance called cholate, which is a naturally occurring substance in the body.
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- 19 Feb, 2024
- 1 location
Clinical Transcriptomics in Systemic Vasculitis (CUTIS)
The histopathology of cutaneous vasculitis will be characterized using a standardized, systematic approach. This approach includes a detailed description of abnormalities and extensive immunophenotyping of cell populations in the epidermal, dermal, and subcutaneous layers of skin. In addition to histologic description, skin biopsy material will be used a source of …
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- 19 Feb, 2024
- 1 location
Psoriasis Specimen BioBank
Such a biobank will be critical to allowing us to deepen and expand existing collaborations between dermatology, rheumatology, immunology, and genetics to better define the genetic and immunological abnormalities in psoriatic disease and conduct studies that lead to personalized medicine approaches to diagnosis, staging, and treatment selection for this common …
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- 19 Feb, 2024
- 1 location
Vessel Wall Magnetic Resonance Imaging to Explore Gender Differences of Intracranial Arterial Wall Changes After Suspected Stroke
We propose a study to prospectively evaluate women and men with stroke using VWI to estimate the prevalence of vessel wall abnormalities leading to stroke. Early detection of vessel wall changes in correlation with modifiable risk factors will help us identify opportunities for early prevention of stroke in women.
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- 19 Feb, 2024
- 1 location
Changes in Bone Quality Sarcopenia and Fat Distribution in HIV/HCV Patients after HCV Therapy
It is unknown if HCV cure with direct-acting antiviral (DAA) therapy ameliorates these abnormalities, and if the degree of improvement is similar for HIV+/HCV+ and HCV+ patients. We will assemble three cohorts: 1) HCV treatment-naïve HIV+/HCV+ coinfected patients initiating DAA therapy, 2) treatment-naïve HCV+ monoinfected patients initiating DAA therapy, and …
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- 19 Feb, 2024
- 1 location
FOLLOW-UP VESSEL WALL MR IMAGING TO EXPLORE SEX-DIFFERENCES OF INTRACRANIAL ARTERIAL WALL CHANGES AND INTRACRANIAL ATHEROSCLEROTIC PLAQUE TREATMENT EFFICACY
We propose a study to prospectively evaluate women and men with stroke using VWI to estimate the prevalence of vessel wall abnormalities leading to stroke. Early detection of vessel wall changes in correlation with modifiable risk factors will help us identify opportunities for early prevention of stroke in women.
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- 19 Feb, 2024
- 1 location
Determination of B-cell responsiveness to the incretin hormones GLP-1 and GIP in Cystic Fibrosis (PRIME)
Detailed studies of insulin secretion in CF are required to achieve this goal since 1) subtle insulin secretion defects may contribute to worsening pulmonary function and nutritional status, 2) treatment of these early abnormalities may be beneficial, and 3) insulin secretion defects are not adequately depicted by oral glucose tolerance …
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- 19 Feb, 2024
- 1 location
Medtronic Evaluation of Multi-Electrode Phased RF Technology in Persistent Atrial Fibrillation
The Phased RF System includes the GENius Multi Channel Radio Frequency Ablation Generator and three anatomically designed, multi-electrode catheters: Pulmonary Vein Ablation Catheter GOLD (PVAC GOLD) Multi-Array Septal Catheter (MASC) Multi-Array Ablation Catheter (MAAC) INCLUSION CRITERIA History of symptomatic persistent or long-standing persistent atrial fibrillation defined as: o Persistent AF: …
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- 19 Feb, 2024
- 1 location
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