Birth Defects Clinical Trials
A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 17 clinical trials
Clinical Transcriptomics in Systemic Vasculitis (CUTIS)
The histopathology of cutaneous vasculitis will be characterized using a standardized, systematic approach. This approach includes a detailed description of abnormalities and extensive immunophenotyping of cell populations in the epidermal, dermal, and subcutaneous layers of skin. In addition to histologic description, skin biopsy material will be used a source of …
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- 19 Feb, 2024
- 1 location
UPCC#01409: Lintuzumab-Ac225 in Older Patients with Untreated AML
This is a phase 1/2 study of a radio-labeled investigational drug, 225Ac-lintuzumab, given in combination with low-dose cytarabine in previously untreated elderly patients with AML. Phase 1 will establish the MTD of fractionated doses of Lintuzumab-Ac225 in combination with low dose cytosine arabinoside, and Phase 2 will help determine the …
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- 08 May, 2025
- 1 location
Vessel Wall Magnetic Resonance Imaging to Explore Gender Differences of Intracranial Arterial Wall Changes After Suspected Stroke
We propose a study to prospectively evaluate women and men with stroke using VWI to estimate the prevalence of vessel wall abnormalities leading to stroke. Early detection of vessel wall changes in correlation with modifiable risk factors will help us identify opportunities for early prevention of stroke in women.
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- 19 Feb, 2024
- 1 location
Changes in Bone Quality Sarcopenia and Fat Distribution in HIV/HCV Patients after HCV Therapy
It is unknown if HCV cure with direct-acting antiviral (DAA) therapy ameliorates these abnormalities, and if the degree of improvement is similar for HIV+/HCV+ and HCV+ patients. We will assemble three cohorts: 1) HCV treatment-naïve HIV+/HCV+ coinfected patients initiating DAA therapy, 2) treatment-naïve HCV+ monoinfected patients initiating DAA therapy, and …
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- 19 Feb, 2024
- 1 location
Determination of B-cell responsiveness to the incretin hormones GLP-1 and GIP in Cystic Fibrosis (PRIME)
Detailed studies of insulin secretion in CF are required to achieve this goal since 1) subtle insulin secretion defects may contribute to worsening pulmonary function and nutritional status, 2) treatment of these early abnormalities may be beneficial, and 3) insulin secretion defects are not adequately depicted by oral glucose tolerance …
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- 19 Feb, 2024
- 1 location
PERI-PROCEDURAL TRANSMURAL ELECTROPHYSIOLOGICAL IMAGING OF SCAR-RELATED VENTRICULAR TACHYCARDIA
We are hopeful that ECGi will provide us a better understanding on the underlying cause of heart rhythm abnormalities in ventricular tachycardia and would like to use ECGi as a clinical tool to improve the success and safety of VT ablation.
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- 19 Feb, 2024
- 1 location
Medtronic Evaluation of Multi-Electrode Phased RF Technology in Persistent Atrial Fibrillation
The Phased RF System includes the GENius Multi Channel Radio Frequency Ablation Generator and three anatomically designed, multi-electrode catheters: Pulmonary Vein Ablation Catheter GOLD (PVAC GOLD) Multi-Array Septal Catheter (MASC) Multi-Array Ablation Catheter (MAAC) INCLUSION CRITERIA History of symptomatic persistent or long-standing persistent atrial fibrillation defined as: o Persistent AF: …
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- 19 Feb, 2024
- 1 location
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