Surgery Clinical Trials
A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 288 clinical trials
Randomized Study of Cranial Blocks for Postoperative Anesthesia to Reduce Pain and Postoperative Opioid Usage
The research study is being conducted to look at the effectiveness of analgesia (pain medication) by scalp nerve block with various medications that will help doctors to more effectively control pain after surgery and for a longer period of time.
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- 19 Feb, 2024
- 1 location
Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer
Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have recurrence. Additional immunotherapeutic agents given before surgery may be greatly reduce recurrence.
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- 19 Feb, 2024
- 1 location
UPCC 09618: Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma
The main purpose of this study is to determine the rate of positive sentinel lymph nodes (i.e. the closest draining lymph node(s) to the primary melanoma site) and to test whether treatment with pembrolizumab before surgery to remove melanoma reduces the rate of positive sentinel lymph nodes in patients with …
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- 19 Feb, 2024
- 1 location
Preoperative use of radiation boost to enhance effectiveness of immune checkpoint blockade therapy in operable breast cancer
We will employ a Simon Two Stage design to evaluate the safety, feasibility, and efficacy of combination radiation boost and a single pembrolizumab infusion prior to definitive surgery.
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- 19 Feb, 2024
- 1 location
Cancer detection rate of Abbreviated (Fast) Breast MRI (AB-MR) after negative Digitial Breast Tomosynthesis in Women status post Conservation Therapy (BCT)
Although mammographic screening is recommended annually, the sensitivity of mammography is limited in these patients due to the post treatment changes from previous surgery and radiation. We propose supplemental screening with an abbreviated form of breast MRI ("fast MRI") examination in addition to mammographic screening, in order to study whether …
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- 19 Feb, 2024
- 1 location
DISSECT-N is an Observational Registry to Assess Real-world Safety and Effectiveness of the Valiant Navion Thoracic Stent Graft in Routine Clinical Practice in Subjects Diagnosed With a Dissection of the Thoracic Aorta
A "Type B" aortic dissection occurs specifically in the descending thoracic aorta. Repair of the dissection via open surgery has historically yielded poor results, and the standard treatment is now thoracic endovascular aneurysm repair (TEVAR). In these minimally invasive procedures, a stent graft is inserted into the aorta via an …
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- 19 Feb, 2024
- 1 location
Treatment for Mixed Urinary Incontinence: Mid-urethral Sling vs. Botox A
The primary objective is to estimate the effect of 100 units of intradetrusor injections of Botulinum toxin A (Botox A ®) compared to mid-urethral sling surgery for the treatment of MUI in 110 women. Participants in the Botox A arm may receive one additional injection of 100 units Botox A …
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- 19 Feb, 2024
- 1 location
A Randomized Placebo-Controlled Study of the Efficacy and Safety of Intracerebral Stem Cells (CTX0E03) in Subjects with Disability Following an Ischemic Stroke
The research study is being conducted to find out if this study drug provides any improvement in the arm and/or leg function affected by the stroke. The study will also gather more information about the safety of the study drug, surgical procedure and equipment used to inject the study drug. …
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- 19 Feb, 2024
- 1 location
CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer
The purposes of this study are to test the effectiveness of the study drug, SGM-101 to allow the doctor who will perform the surgery to remove your cancer to see better which tissue is cancer and which is healthy so that the surgery can be performed more precisely to get …
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- 19 Feb, 2024
- 1 location
Study to Evaluate Imaging Feasibility, Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes Primary Tumors and Tumor Margins in Patients with Solid Tumors
The main purpose of this study is to investigate whether ONM-100 can be used to image primary tumors and metastatic lymph nodes at time points earlier than 24 ±8 hours in patients undergoing routine surgery of their solid cancers and whether the diagnostic performance to detect metastatic lymph nodes can …
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- 19 Feb, 2024
- 1 location