Surgery Clinical Trials
A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 288 clinical trials
CYTOSORB REDUCTION OF FREE HEMOGLOBIN/ACUTE KIDNEY INJURY (AKI) DURING CARDIAC SURGERY - REFRESH II
Reliance Agreement Request - Please refer to WIRB
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- 19 Feb, 2024
- 1 location
UPCC 07518: Pembrolizumab in combination with chemotherapy and image-guided surgery for malignant pleural mesothelioma (MPM).
The study is a single-arm phase I trial to evaluate the safety, feasibility, and preliminary efficacy of the addition of pembrolizumab and image-guided resection to surgical therapy and chemotherapy for MPM
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- 19 Feb, 2024
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A Study to Evaluate the Safety and Feasibility of Exablate Model 4000 Type-2 to temporarily mediate Blood-Brain Barrier Disruption (BBBD) in patients with suspected infiltrating glioma in the setting of planned surgical interventions
The goal of this prospective, non-randomized, single-arm study is to evaluate the safety and feasibility of using ExAblate Model 4000 Type-2 Neuro-System as a tool to disrupt the blood brain barrier in a temporary and localized fashion in patients with suspected infiltrating glioma undergoing planned surgical interventions.
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- 19 Feb, 2024
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A Randomized Placebo Surgery Controlled Double-blinded Multi-center Phase 2 Clinical Trial Evaluating Efcacy and Safety of VY-AADC02 in Advanced Parkinsons Disease with Motor Fluctuations
It is necessary to evaluate the benet of a new, experimental treatment by having a similar group for comparison (placebo). PD studies in the past have used a placebo surgery for this reason.Other than the surgical team, neither you nor the rest of the study team will know if you …
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- 19 Feb, 2024
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A Study to Evaluate the Safety and Efficacy of Image Guided Surgery using Indocyanine Green for Intramolecular Imaging of Solid Tumors Compared to Standard of Care (TumorGlow) (PRIME)
Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove primary tumor nodules in a satisfactory manner as well as lingering metastases in sentinel lymph nodes.
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- 19 Feb, 2024
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A Phase III multi-center double-blind randomized withdrawal study of LCI699 following a 24 week single-arm open-label dose titration and treatment period to evaluate the safety and efficacy of LCI699 for the treatment of patients with Cushings disease (PRIME)
The study aims to confirm the long-term efficacy and safety of LCI699 for the treatment of patients with Cushing's disease who have had had surgery that has not been successful, or are not a good surgical candidate, or refuse surgery, and have not received radiation treatment for this condition within …
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- 19 Feb, 2024
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Towards predicting the analgesic response to ibuprofen following third-molar extraction
The purpose of this study is to see if there are substances in your blood and urine which we will take both before and after your wisdom teeth surgery that can tell us how you personally will respond to ibuprofen in comparison to placebo (an inactive sugar pill). We will …
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- 19 Feb, 2024
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A Prospective Observational Study of Outcomes from Proximal Thoracic Aortic Disease
The purpose of this registry is to collect real-time data for those patients who have aortic disease of their ascending (top) aorta and the aortic arch (curved area where the vessels that supply the brain with blood). The current treatment requires open surgery or a hybrid procedure (open surgery with …
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- 19 Feb, 2024
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Prospective Clinical Study of Tri-planar TarsometatarsL (TMT) ArthrodesIs with Early Weight-Bearing after Lapiplasty Procedure
The study will also determine if putting weight on your foot shortly after surgery affects how well your bone heals (fuse) after the Lapiplasty procedure. Information about pain caused by the bunion and how whether your pain improves and your satisfaction with the procedure will also be collected throughout the …
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- 19 Feb, 2024
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The effect of Liposomal Bupivacaine on the quality of recovery in patients undergoing shoulder arthroscopy
The research study is being conducted to see if using liposomal bupivacaine for the interscalene block will improve the patient pain control and the whole patient’s experience 48 hours after surgery when compared to using the regular Marcaine in addition to the dexamethasone.
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- 19 Feb, 2024
- 1 location