Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 188 clinical trials
A Phase 1 Study of the Highly-selective RET

This is a phase 1 study with Highly-selective RET inhibiter, Blu-667, in patients with Thyroid Cancer, Non-Small cell lung cancer and other advanced solid tumors. The study will be conducted at multiple centers in the United States and Europe.

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  • 19 Feb, 2024
  • 1 location
Genomic Epigenetic Proteomic Metabolomic and Immunologic Characterization of Metastatic Neuroendocrine Tumors Surviving Transarterial Embolotherapy

mNET is commonly treated with TACE or TACE. mNET cells can survive TACE or TARE ischemic conditions. In this study, we will biopsy mNETs being treated with TACE or TARE prior to treatment, after treatment, and again at recurrence to characterize the metabolic, immunologic, and genetic profile of the cells …

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  • 19 Feb, 2024
  • 1 location
UPCC 24116: A Phase II Pilot Trial of Hydroxychloroquine Everolimus or the Combination for Prevention of Recurrent Breast Cancer

The main purpose of this study is to: 1) determine the feasibility of giving hydroxychloroquine, everolimus or the combination to people with disseminated tumor cells detected in their bone marrow. 2) determine how tolerable these drugs are in people who have completed treatment for breast cancer. 3) determine how well …

  • 0 views
  • 19 Feb, 2024
  • 1 location
An Open-Label Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Buccal Soluble Film (DBSF) in Adult Subjects With Epilepsy.

You are being asked to be in this study because you have epilepsy and you take epilepsy medication. Aquestive Therapeutics (the study Sponsor) has begun a research study of an investigational drug called Diazepam Buccal Soluble Film or DBSF as a possible treatment for patients with epilepsy. An investigational drug …

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  • 19 Feb, 2024
  • 1 location
A Pilot Single dose Open-Label Study of OTL38 Injection (OTL38) for Intra-Operative Imaging of Folate Receptor Positive Ovarian Cancer Comparing Camera Imaging Systems

This study will provide information about the suitability of other camera systems that may be used to better assess ovarian cancers targeted by OTL38.

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  • 19 Feb, 2024
  • 1 location
UPCC 10519 / I5B-MC-Y001: An Open-Label Multi-Center Patient Access Program of Olaratumab for the Treatment of Soft Tissue Sarcoma

The purpose of this program is to allow patients who, in consultation with their treating physician, feel it is in their best interest to continue to receive olaratumab. Only patients with soft tissue sarcoma who are already being treated with olaratumab may enter this program.

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  • 19 Feb, 2024
  • 1 location
UPCC 11917: A Dose-Finding Phase 1 Study of TAS-120 in Patients With Advanced Solid Tumors With or Without Fibroblast Growth Factor/Receptor (FGF/FGFR)-Related Abnormalities followed by a Phase 2 Study in Patients with Advanced Solid Tumors with FGF/FGFR-Related Abnormalities

Request for collaborative review: WIRB serving as IRB of record.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Phase 2 Trial of AGEN2034 (anti-PD-1) as a Monotherapy of Combination Therapy with AGEN1884 (anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer (Second Line) - RaPiDS

If stored tumor specimen is not available, a fresh biopsy will be required.

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  • 19 Feb, 2024
  • 1 location
FES PET/CT in Endocrine Refractory Breast Cancer

  Some patients may also undergo a second FES PET/CT scan, at the time of suspected progression of disease to compare for changes in FES uptake measures.   Patients may undergo primary tumor or metastatic biopsy, as part of their clinical care.  Patients may also be enrolled in a separate …

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  • 19 Feb, 2024
  • 2 locations
Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation with Focal Impulse and Rotor Modulation Guided Procedures

An algorithm that has been licensed for use with a novel mapping technology (RhythmView, Abbott Electrophysiology (Topera, Inc.), Menlo Park, CA) for analyzing atrial recordings during human AF, finding that greater than 95% of cases demonstrate either a rapidly spinning rotor (small circuit) or very rapid focal impulse formation.

  • 0 views
  • 19 Feb, 2024
  • 1 location