Dementia Clinical Trials
A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 34 clinical trials
Conceptual Processing in Alzheimer’s Disease
The purpose of this study is to evaluate memory, language and cognitive difficulties in patients with AD. AD is a neurological disease where a specific part of the brain is not functioning well. A clinical diagnosis of AD needs to be confirmed in all participants prior to participation in the …
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- 19 Feb, 2024
- 1 location
The Neural Basis for Frontotemporal Degeneration
The purpose of this research study is to develop a better understanding of the genetic causes for frontotemporal degeneration (FTD), as well as Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA). These conditions include difficulty with language and speaking, organization and planning, memory, and/or a behavior or personality change. …
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- 19 Feb, 2024
- 1 location
Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) Protocol
Clinical/cognitive, imaging, biomarker, and genetic characteristics will be assessed across three cohorts: (1) early onset Alzheimer's Disease (EOAD) participants, (2) early onset non-Alzheimer's Disease (EO-nonAD) participants,and (3) cognitively normal (CN) control participants.
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- 19 Feb, 2024
- 1 location
Alzheimers Disease Neuroimaging Initiative 3 (ADNI3)
It is a non-treatment clinical research study to discover, optimize, standardize, and validate clinical trial measures and biomarkers used in ongoing AD research.Data from this research will help determine the best measures for diagnosis and disease monitoring , which will be used to accelerate the testing of therapeutic interventions and …
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- 19 Feb, 2024
- 1 location
Clinical Core Alzheimer's Disease Core Center (ABC)
The purpose of this study is to collect, store and analyze cognitive data and biological samples, such as blood and MRI imaging, from individuals without symptoms of memory loss and/or dementia. Our goal is to improve our understanding of age-associated brain changes and our ability to diagnosis and treat brain …
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- 19 Feb, 2024
- 1 location
A randomized double-blind placebo-controlled parallel group study to evaluate the efficacy and safety of CNP520 in participants at risk for the onset of clinical symptoms of Alzheimers Disease (AD)
The study will enroll cognitively unimpaired individuals who are between the ages of 60-75 years with at least one APOE4 allele (HMs or HTs) and, if HTs, with evidence of elevated brain amyloid. Cognitively unimpaired subjects defined as having a Mini-Mental State Examination (MMSE) total score greater than or equal …
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- 19 Feb, 2024
- 1 location
A Pilot Study to Evaluate the Effect of CT1812 Treatment on A-beta Oligomer Displacement into CSF in Subjects with Mild to Moderate Alzheimer's Disease
Cognition Therapeutics is developing an oral formulation of CT1812 to treat AD and mild cognitive impairment. This is a multi-center, Phase 1b, randomized, double-blind, placebo-controlled parallel-group trial in adults with mild to moderate AD, sponsored by the NIH.
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- 19 Feb, 2024
- 1 location
18-Month Study With an Open-Label Extension Phase to Confirm Safety and Efficacy of BAN2401 in Subjects With Early Alzheimers Disease
A total of 1566 subjects will be randomized in the Core Study across 2 treatment groups, (placebo and BAN2401 10 mg/kg, biweekly) according to a fixed 1:1 (placebo:BAN2401) schedule. Randomization will occur across 2 clinical subgroups (MCI due to AD/prodromal AD or mild AD dementia), and will be reasonably balanced, …
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- 19 Feb, 2024
- 1 location
Chronic insomnia and CSF markers of dementia
The purpose of this study is to identify the relationship between chronic sleep disturbance and chemicals in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.
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- 19 Feb, 2024
- 1 location
Healthy Patterns Sleep Intervention for Persons with Memory and Sleep Problems and their Caregivers
The Healthy Patterns Study intervention is a home-based activity intervention designed to introduce activities and education that promote healthy sleeping habits and improve well-being for those suffering with memory and sleep issues . Principal Investigator: Nancy A. Hodsgon, PhD, RN, FAAN, Nursing School, University of Pennsylvania
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- 19 Feb, 2024
- 1 location