Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 56 clinical trials
Featured trial
DCPMS: Dialated Cardiomyopathy Precision Medicine Study

This study aims to understand the effects of potential familial/genetic links in an otherwise unclear origin of a patient's heart disease.

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  • 19 Feb, 2024
  • 1 location
Featured trial
Electrogram Guided Myocardial Advanced Phenotyping (EMAP) Study for patients recently diagnosed with cardiomyopathy

This study is enrolling newly diagnosed heart failure (within 6 months from diagnosis) patients with no known cause for their heart disease. We are utilizing already used technology, voltage mapping capabilities used in electrophysiology procedures, to more directly target weaker areas of the left and right ventricles. our physicians would …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Featured trial
LIFE Study: Entresto TM in Advanced Heart Failure

This study aims to understand the benefits/risks of Entresto in NYHA III-IV patients.

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  • 19 Feb, 2024
  • 1 location
Featured trial
Normal Donor Human Bone Marrow Donation for Research

We are looking for healthy volunteers to donate bone marrow for research purposes. The Stem Cell & Xenograft Core provides bone marrow to laboratories on Penn’s campus researching leukemia and other blood disorders

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  • 19 Feb, 2024
  • 1 location
AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke

Reliance Agreement Request

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  • 19 Feb, 2024
  • 1 location
Multicenter open-label study to evaluate efficacy of gadobutrolenhanced cardiac magnetic resonance imaging (CMRI) for detection of significant coronary artery disease (CAD) in subjects with known or suspected CAD by a blinded image analysis

The primary efficacy objectives of this study are to demonstrate that sensitivity and specificity of gadobutrol-enhanced CMRI exceed prespecified minimum performance thresholds (MPT) of 60% and 55%, respectively and to show superior sensitivity over unenhanced wall motion CMRI at vasodilator rest/stress for the detection of significant coronary artery disease (CAD) …

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  • 19 Feb, 2024
  • 1 location
Cardiovascular Inflammation Reduction Trial (CIRT): A randomized double-blind placebo controlled event-driven trial of weekly low-dose methotrexate (LDM) in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with type 2 diabetes or metabolic syndrome

The combination of problems tends to occur together and raise your risk of heart disease and diabetes. Methotrexate is a drug commonly used to reduce inflammation (pain and swelling) in the joints of people with rheumatoid arthritis.

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  • 19 Feb, 2024
  • 1 location
(PREDICT) A Multi-Center Study in Patients Undergoing Anthracycline-Based Chemotherapy to Assess the Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment

There is a growing recognition that although survival has improved, many long-term side effects including cardiac complications limit quality of life and life span after cancer. Additionally, cardiac disease remains one of the most common illness affecting all patients, including those with cancer. As a result, there is a mandate …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Open-Labeled Trial Of Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Heart Transplants From Hepatitis C-Positive Donors

Long-term survival is superior for patients receiving a heart transplant, and VADs are not an option for patients with several forms of end-stage heart disease (i.e., arrhythmia disorders). Thus there is a critical need to expand the pool of heart donors in order to save more lives from end-stage heart …

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  • 19 Feb, 2024
  • 1 location
Medtronic Evaluation of Multi-Electrode Phased RF Technology in Persistent Atrial Fibrillation

The Phased RF System includes the GENius Multi Channel Radio Frequency Ablation Generator and three anatomically designed, multi-electrode catheters: Pulmonary Vein Ablation Catheter GOLD (PVAC GOLD) Multi-Array Septal Catheter (MASC) Multi-Array Ablation Catheter (MAAC) INCLUSION CRITERIA History of symptomatic persistent or long-standing persistent atrial fibrillation defined as: o Persistent AF: …

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  • 19 Feb, 2024
  • 1 location