Heart Disease Clinical Trials

Open-Labeled Trial Of Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Heart Transplants From Hepatitis C-Positive Donors

Long-term survival is superior for patients receiving a heart transplant, and VADs are not an option for patients with several forms of end-stage heart disease (i.e., arrhythmia disorders). Thus there is a critical need to expand the pool of heart donors in order to save more lives from end-stage heart …

Medtronic Evaluation of Multi-Electrode Phased RF Technology in Persistent Atrial Fibrillation

The Phased RF System includes the GENius Multi Channel Radio Frequency Ablation Generator and three anatomically designed, multi-electrode catheters: Pulmonary Vein Ablation Catheter GOLD (PVAC GOLD) Multi-Array Septal Catheter (MASC) Multi-Array Ablation Catheter (MAAC) INCLUSION CRITERIA History of symptomatic persistent or long-standing persistent atrial fibrillation defined as: o Persistent AF: …

Testing Novel Pharmacogenetic and Adherence Optimization Treatments to Improve the Effectiveness of Smoking Cessation Treatments for Smokers with HIV

Development of a reliable means for functional assessment of liver performance after Fontan operation: dual cholate clearance assay

With vastly improved survival for babies born with congenital heart disease (CHD), there is increasing attention on long-term outcomes in adulthood, especially those born with severe forms of CHD. One area of intense research is liver disease in Fontan patients, the nature of which is incompletely understood.

Multicenter randomized double-blind parallel-group add-on superiority study to compare the efficacy and safety of ponesimod to placebo in subjects with active relapsing multiple sclerosis who are treated with dimethyl fumarate (Tecfidera )

This is a study to find out whether patients with active forms of Relapsing Multiple Sclerosis (RMS) who are treated with dimethyl fumarate (Tecfidera®) can be treated better by the addition of ponesimod (study drug). The purpose is also to evaluate the effect on disability and the safety of these …

Efficacy of DE-MRI-Guided Fibrosis Ablation vs. Conventional Catheter Ablation of Atrial Fibrillation: The DECAAF II Study

You are being asked to participate in this study because you have atrial fibrillation and are planning to undergo an ablation procedure to treat this heart rhythm irregularity.