Pneumonia Clinical Trials

Measurement of Pulmonary Inflammation Using F-NOS Positron Emission Tomography (PET/CT) in E-cigarette Users

This is a 1 – 2 month study examining the extent of lung inflammation between e-cigarette smokers, cigarette smokers, and non-smokers using a new radio tracer, FNOS. FNOS is an experimental radio tracer used to look for inflammation in different parts of the body.

A PHASE III RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED STUDY OF AEROVANC FOR THE TREATMENT OF PERSISTANT METHICILLIN-RESISTANT Staphylococcus aureus LUNG INFECTION IN CYSTIC FIBROSIS PATIENTS; SAV005-04

TBD

Secondary Distribution of HIV Self-Tests: an Innovative Strategy for Promoting Partner Testing and Reducing Risk

Changes in Bone Quality Sarcopenia and Fat Distribution in HIV/HCV Patients after HCV Therapy

Coinfection with hepatitis C virus (HCV) is common among HIV infected patients. HIV exacerbates HCV-related metabolic complications, and coinfected patients have a higher risk of sarcopenia, visceral adiposity, hepatic steatosis, and bone fracture than those with HCV alone, HIV alone, or uninfected persons. Understanding these associations in HIV+/HCV+ patients, how …

HOPE in Action Prospective Multicenter Clinical Trial of HIV+ Deceased Donor Kidney Transplants for HIV+ Recipients

Use of an HIV+ deceased donor could increase the risk of death, transplant-related or HIV-related complications; alternatively with effective antiretroviral treatment and careful HIV+ donor selection, these risks may be comparable to kidney transplant using an HIV-negative donor. We hypothesize that receiving a kidney transplant from an HIV+ donor will …

Testing Novel Pharmacogenetic and Adherence Optimization Treatments to Improve the Effectiveness of Smoking Cessation Treatments for Smokers with HIV

The research study is being conducted to examine the effects of personalized smoking cessation medication treatment in order to help people with HIV/AIDS to quit smoking. During the study, participants will take either varenicline (brand name Chantix®) or use the nicotine patch, and they will receive smoking cessation therapy with …

MRI Assessment of Hip Fracture Risk and Therapy Response in HIV/HCV Coinfection

Project Summary Within a year of hip fracture 20-30% of patients die, and 50% percent lose the ability to walk. A consensus exists that infection with the human immunodeficiency virus (HIV) or the hepatis C virus (HCV) increases the likelihood of fracture risk. Co-infection with HIV and HCV is prevalent …

Evaluation of in vivo Neuroinflammation Using 18F-NOS (PET/CT) in HIV Positive and Negative Subjects with Opioid Use Disorder and Healthy Controls

Study Purpose: The goal of this study is to learn more about how opiate use and HIV affects inflammation in the brain. We will study this using a type of Positron Emission Tomography (PET/CT) scan using a radioactive imaging drug called 18F-NOS that can be used to measure inflammation in …

Technology for Detection of SARS-Cov-2 in HIV-Positive Cancer Patients

The main purpose of this study is to try a new type of laboratory test for COVID-19 (also called SARS-CoV-2 or novel coronavirus).  COVID-19 is a new disease, so not enough is known about it yet.  This study hopes to collect more information about who is most as risk from …

Using Natural Language Processing to Identify Depression in Patients with HIV

The purpose of this study is to develop algorithms that may help detect depressive symptoms in social media posts, specifically among men who have sex with men and who have HIV.