Allergy Clinical Trials

A listing of Allergy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 327 clinical trials
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T-Cell Response to Vaccination

The purpose of this study is to see how your body responds to a vaccine and how your body forms a protective response after vaccination. In this study we will use the yellow fever vaccine, an FDA approved vaccine that is commonly given to people traveling to certain parts of …

  • 0 views
  • 10 Dec, 2025
  • 1 location
UPCC 02419: An Open-label Single Arm Phase 2 Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285) A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor in Patients with Advanced Systemic Mastocytosis

When increased in number or abnormal in function they release their contents resulting in allergic reactions and other related symptoms, which are also associated with mastocytosis.

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  • 19 Feb, 2024
  • 1 location
Multicenter open-label study to evaluate efficacy of gadobutrolenhanced cardiac magnetic resonance imaging (CMRI) for detection of significant coronary artery disease (CAD) in subjects with known or suspected CAD by a blinded image analysis

The primary efficacy objectives of this study are to demonstrate that sensitivity and specificity of gadobutrol-enhanced CMRI exceed prespecified minimum performance thresholds (MPT) of 60% and 55%, respectively and to show superior sensitivity over unenhanced wall motion CMRI at vasodilator rest/stress for the detection of significant coronary artery disease (CAD) …

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  • 19 Feb, 2024
  • 1 location
Comparing the effects of Oral Contraceptive Pills versus Metformin in the medical management of overweight/obese women with Polycystic Ovary Syndrome

The combination of OCP and metformin (OCP, through lowering androgens, and metformin, through improvement in insulin sensitivity) will likely decrease the prevalence of MetS, thereby altering the risk profile for the development of diabetes and possible cardiovascular disease (CVD) in young women with PCOS.

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  • 19 Feb, 2024
  • 1 location
A PHASE II STUDY EVALUATING THE EFFICACY AND SAFETY OF NIRAPARIB AND TUMOR-TREATING FIELDS IN RECURRENT GLIOBLASTOMA

Tumors harboring such genomic alterations have been described as maintaining a state of BRCAness, i.e. a phenocopy of BRCA1 and BRCA2 mutation that may render the cells sensitive to treatment with PARP inhibition.

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  • 19 Feb, 2024
  • 1 location
Detection of cell-free circulating tumor DNA in patients with glioblastma undergoing treatment with first-line chemoradiotherapy

However, there are currently no published studies that have used a high sensitivity DNA detection assay to quantify cfDNA in patients with GBM. The ability to reliably detect and quantify cfDNA in GBM as a surrogate of tumor burden and disease activity would lead to significantly improved clinical care for …

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  • 19 Feb, 2024
  • 1 location
Investigation of the Effect of Branched Chain Amino Acids on Fat-Induced Insulin Resistance in Healthy Adults.

This protocol will determine whether excess BCAAs worsen free fatty acid-induced insulin resistance. Following a small scale dose-confirmation study, insulin sensitivity in response to low-dose lipid infusion will be compared across simultaneous administrations of the 3 BCAAs, leucine alone, valine alone, or control to better understand the mechanistic contribution of …

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  • 19 Feb, 2024
  • 1 location
UPCC 34810 The Cardiovascular Effects of Sunitinib Therapy: Off-Target Changes in Cardiac Metabolism and Ventricular-Vascular Mechanics (CREST)

The goal of this multi-center pilot study is to characterize the cardiovascular changes that occur with sunitinib through a detailed examination of: 1) sensitive echocardiographic measures of cardiac function; 2) comprehensive measures of arterial function and left ventricular afterload; 3) biomarkers reflective of the pathophysiologic alterations.

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  • 19 Feb, 2024
  • 1 location
CMT Subtype Biomarkers and Outcome Measures

In order to prepare for clinical trials for CMT, there is ongoing work to develop more sensitive outcome measures, and there is a need for complementary biomarkers, particularly target engagement measures that can be used in clinical trials for candidate therapies.

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  • 19 Feb, 2024
  • 1 location
Autism Spectrum Program of Excellence

The goal of the ASPE study is to investigate the genetic basis of Autism spectrum disorder (ASD) and autism-related traits.Individuals 3 years old or older with a diagnosis (or suspected diagnosis) of autism spectrum disorder without intellectual disability may be eligible to participate. We are also recruiting individuals with a deletion or …

  • 0 views
  • 19 Feb, 2024
  • 1 location