Congestive Heart Failure Clinical Trials
A listing of Congestive Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 29 clinical trials
BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in Heart Failure
The purpose of the study is to compare how amlodipine versus metoprolol effect blood pressure in people with HFpEF. While hypertension is the most common risk factor for HFpEF, there is little evidence on the potential role of common antihypertensive medications, specifically calcium channel blockers (like amlodipine) and β-blockers …
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- 19 Feb, 2024
- 1 location
A Clinical Study to Evaluate Ambulatory Counterpulsation for the Treatment of Advanced Heart Failure: A Feasibility Study
The purpose of this study is to: assess if the iVAS can help improve blood circulation, gain a better understanding of how this device could impact your health, determine human interaction with the device, and assess the portability of this device.
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- 19 Feb, 2024
- 1 location
Early Feasibility Study of the AccuCinch Ventricular Repair System in Patients with Heart Failure and Reduced Ejection Fraction (HFrEF)
This investigational (experimental) device is designed to treat patients who are experiencing symptoms of heart failure due to a dilated left ventricle (heart chamber that pumps blood).
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- 19 Feb, 2024
- 1 location
Effect of Organic Nitrates and Hydralazine on Wave Reflections and Left Ventricular Structure and Function in Heart Failure with Preserved Ejection Fraction
The purpose of this study is to test the effect of prolonged therapy (24 weeks) with isosorbide dinitrate ± hydralazine on arterial wave reflections, exercise capacity, left ventricular (LV) mass/fibrosis and diastolic function in patients with Heart Failure and Preserved Ejection Fraction (HFPEF). This is a double-blind, placebo-controlled pilot randomized …
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- 19 Feb, 2024
- 1 location
Attain StarFix Model 4195 LV Lead Extraction Study
The purpose of this study is to characterize the removability of the Attain StarFix®Model 4195 Left Ventricular (LV) Lead (StarFix®). The goal of the trial is to evaluate the lead removal success in patients that are indicated for left ventricular lead removal. This study is required by the Food and …
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- 19 Feb, 2024
- 1 location
Open-Labeled Trial Of Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Heart Transplants From Hepatitis C-Positive Donors
Since 2006, there has been a 50% increase in the number of adults added to the heart transplant waitlist in the US. Yet the persistent organ donor shortage has led to only a 25% increase in the number of transplants, and a 25% increase in the number of patients removed …
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- 19 Feb, 2024
- 1 location
Strategic Management to Optimize Response to Cardiac Resynchronization Therapy
Potential changes in implant technique (optimizing lead position for position rather than electrical performance) as well as potential changes in the practice of medicine when treating heart failure patients. Accordingly, a randomized controlled trial was chosen. This study design helps assure that two comparable patient populations are obtained while mitigating …
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- 19 Feb, 2024
- 1 location
AN EXPLORATORY OPEN-LABEL PROOF-OF-CONCEPT PHASE 2A STUDY OF MAVACAMTEN (MYK-461) IN PARTICIPANTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFpEF) AND CHRONIC ELEVATION OF CARDIAC TROPONIN I AND/OR NT-PROBNP
This is a multicenter, exploratory, open-label study to explore the efficacy and/or pharmacodynamic effect, PK, safety, and tolerability of mavacamten in approximately 35 ambulatory participants with symptomatic HFpEF and elevated cTnI and/or elevated NT-proBNP as defined in inclusion/exclusion criteria. The study will include an up to 7-week screening period (with …
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- 19 Feb, 2024
- 1 location