Congestive Heart Failure Clinical Trials

A listing of Congestive Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 29 clinical trials
A Prospective Randomised Trial of Early LV Venting Using Impella CP for Recovery in patients with cardiogenic managed with VA ECMO (REVERSE)

Veno-arterial (VA) extra-corporeal membrane oxygenation (ECMO) is indicated as a haemodynamic rescue strategy in decompensated acute or chronic heart failure presenting as cardiogenic shock. VA ECMO has a number of effects on the circulation including (i) perfusing end-organs, (ii) ventricular unloading, and (iii) improved coronary perfusion.

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  • 19 Feb, 2024
  • 1 location
Changes in the lymphatic system on MR Lymphangiography (MRL) in patients with congestive heart failure (CHF).

Observational study of adults with congestive heart failure and normal healthy participants using Magnetic Resonance Imaging (MRI) to compare changes in the lymphatic system (thin tubes and lymph nodes that run throughout the body).

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  • 19 Feb, 2024
  • 1 location
The Effect of Potassium Nitrate [KNO3] on Exercise Capacity in Heart Failure Patients.

This study will test whether Potassium Nitrate (KNO3) will improve how people with HFpEF [Diastolic Heart Failure] can exercise. In HFpEF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to becoming tired and short …

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  • 19 Feb, 2024
  • 1 location
DEVELOPING ORAL LT3 THERAPY FOR HEART FAILURE (DOT3HF)

Parallel, Randomized, Double-Blind, Placebo-Controlled Crossover Clinical Trial The primary objective is to evaluate the safety of oral LT3 in heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) The secondary objective is to evaluate the feasibility and preliminary efficacy outcomes of oral LT3 therapy …

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  • 19 Feb, 2024
  • 1 location
Dapagliflozin Effect on symptoms and blomarkers in patients with Heart Failure (DEFINE-HF)

The purpose of this study is to find out if a drug called dapagliflozin would be effective in improving the blood tests and symptoms related to your heart failure.

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  • 19 Feb, 2024
  • 1 location
Transcatheter Aortic Valve Replacement to UNload the Left ventricle in patients with ADvanced heart failure

Randomized (flip of the coin 50/50) study of heart failure (HF) patients with moderate aortic valve stenosis (narrowing) will be either treated with a transcatheter valve replacement (TAVR) or continue with medical management.

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  • 19 Feb, 2024
  • 1 location
BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in Heart Failure

The purpose of the study is to compare how amlodipine versus metoprolol effect blood pressure in people with HFpEF.   While hypertension is the most common risk factor for HFpEF, there is little evidence on the potential role of common antihypertensive medications, specifically calcium channel blockers (like amlodipine) and β-blockers …

  • 0 views
  • 19 Feb, 2024
  • 1 location
A Clinical Study to Evaluate Ambulatory Counterpulsation for the Treatment of Advanced Heart Failure: A Feasibility Study

The purpose of this study is to: assess if the iVAS can help improve blood circulation, gain a better understanding of how this device could impact your health, determine human interaction with the device, and assess the portability of this device.

  • 0 views
  • 19 Feb, 2024
  • 1 location
A Clinical Study to Evaluate Ambulatory Counterpulsation for the Treatment of Advanced Heart Failure: A Feasibility Study

The purpose of this study is to: assess if the iVAS can help improve blood circulation, gain a better understanding of how this device could impact your health, determine human interaction with the device, and assess the portability of this device.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Early Feasibility Study of the AccuCinch Ventricular Repair System in Patients with Heart Failure and Reduced Ejection Fraction (HFrEF)

This investigational (experimental) device is designed to treat patients who are experiencing symptoms of heart failure due to a dilated left ventricle (heart chamber that pumps blood).

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  • 19 Feb, 2024
  • 1 location