Found 706 clinical trials
Genetics of Alcohol Dependence and Withdrawal in African Americans
The purpose of this study is to learn things that will help us better understand alcohol dependence, other kinds of substance dependence, and aspects of personality and behavior in African Americans. DNA, the material that carries genetic instructions, will be taken from blood, and used to study genes for these …
Phase 1 Open-Label Study to Determine the Safety and Tolerability of AVID200, a Transforming Growth Factor B Inhibitor, in Diffuse Cutaneous Systemic Sclerosis
This study is being done to learn more about the safety of the study drug, AVID200, and to find out more about the effects of different study drug doses in people with scleroderma. AVID200 is referred to as an investigational drug because it is in the early stages of development …
A Randomized, Double-Blind, Placebo-Controlled Multiple Ascending Dose Study of Intravenous ATYR1923 in Patients with Pulmonary Sarcoidosis
This study is being done to learn more about the safety of an investigational drug called ATYR1923, and to find out more about the effects of different doses of this drug on the lungs of people who have pulmonary sarcoidosis. "Investigational" means that it is not approved by the United …
Neurobiology of Caregiving in New Mothers (Children between 0-3 years old)
This study is to learn more about social processes on a behavioral and brain level in new mothers. If you are eligible, there are three in person visits, one consisting of an fMRI scan. MRI uses magnetic fields to take pictures of the brain. MRI does not use X-rays and …
INGEST study
14.00 Normal 0 false false false EN-US X-NONE X-NONE We are looking for healthy volunteers to participate in a study to see if a particular type of medication (statin) has an impact on the kind of bacteria that are found in the gut, and if the gut bacteria affects how …
Study to Evaluate the Safety and Efficacy of Upadacitinib in Giant Cell Arteritis: SELECT-GCA
The main purpose of this study is to understand how well giant cell arteritis (also known as temporal arteritis; GCA) responds to an investigational drug called upadacitinib. Upadacitinib is being tested to find out if it is safe and effective in treating GCA. An investigational drug is one that is …
A Randomized, Double-Blind, Placebo Controlled Study to Evaluate Efficacy and Safety of Nefecon in Patients with Primary IgA Nephropathy at Risk of Progressing to End-Stage Renal Disease (NefIgArd)
The research study is being conducted to see how well the investigational drug, Nefecon, works for the treatment of your kidney disease and more specific for patients with "primary immunoglobulin A nephropathy," called IgAN.
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS-IgAN)
This study will use a new investigational study drug called OMS721 in people with Immunoglobulin A (IgA) Nephropathy. This kidney disease produces abnormal amounts of a protein called IgA in the kidney that damage the filtering units or glomeruli. Glomeruli are tiny filtering units in the kidney that remove excess …
The PATCH trial for Healthcare Workers (Prevention and Treatment of COVID-19 with hydroxychloroquine)
The PATCH trial tests hydroxychloroquine as a treatment in patients with COVID-19 and a preventative medication in health care workers at high risk of contracting COVID-19.
The PATCH trial for patients Quarantined at Home (Prevention and Treatment of COVID-19 with hydroxychloroquine)
A double-blind placebo controlled trial of high dose hydroxychloroquine (HCQ) as a treatment for COVID-19 positive patients who are quarantined at home
