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Found 706 clinical trials

The effect of Liposomal Bupivacaine on the quality of recovery in patients undergoing shoulder arthroscopy

The research study is being conducted to see if using liposomal bupivacaine for the interscalene block will improve the patient pain control and the whole patient’s experience 48 hours after surgery when compared to using the regular Marcaine in addition to the dexamethasone.

18-99 years
All
Phase 3

The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer Patients

The research study is being conducted secondary and after your completion of the primary study (Effect of Radiation Therapy on Sleepiness and Activity in Prostate and Breast Cancer Patients). The purpose of the current study is to assess the effectiveness of a behavioral treatment for insomnia (also known as Cognitive …

18-99 years
All
Phase N/A

Physiologic MR Imaging in Distinguishing Benign from Malignant Salivary Gland Tumors

The purpose of this research study is to help identify the difference between cancerous and non-cancerous salivary gland tumors for improving treatment strategies and also aid in the prediction of disease progression. It is important to determine whether the salivary gland tumor is cancerous prior to operation because this information …

18-99 years
All
Phase N/A

A Phase I/II Study of Ixazomib and Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma

The purpose of this study is to see whether the addition of ixazomib to ibrutinib chemotherapy is effective in treating people who have relapsed or refractory mantle cell lymphoma and to examine the side effects associated with ixazomib in combination with ibrutinib.

18-99 years
All
Phase 2

A Phase I/II study of lutetium (177Lu)-lilotomab satetraxetan (Betalutin) antibody-radionuclide-conjugate for treatment of relapsed non-Hodgkin lymphoma

Non-Hodgkin lymphoma is a disease that can be treated effectively with chemotherapy and immunotherapy, but relapses can occur. The purpose of this study is to research the use of a new radioimmunotherapy drug called Betalutin®. Betalutin® is made by using a new antibody, called lilotomab, and attaching a radioactive molecule …

18-90 years
All
Phase 2

Open-label Extension Study to Evaluate the Long-term Safety of Cenobamate Adjunctive Therapy in Subjects with Primary Generalized Tonic- Clonic Seizures

The research study is being conducted to evaluate the long-term safety and tolerability of cenobamate for Primary Generalized Tonic-Clonic (PGTC) seizures

18-99 years
All
Phase 3

Phase 1 Study of Convalescent Plasma for Severely ill Mechanically Ventilated Participants with COVID-19 Caused by SARS-CoV-2

Only patients admitted to the hospital and on a ventilator for treatment of COVID-19 are eligible to participate. The purpose of this study is to develop a possible new treatment for COVID-19 disease which uses antibodies against this virus. Antibodies are natural proteins made by the body that attack viruses and …

18 years and older
All
Phase 1

Transforming Research and Clinical Knowledge in Traumatic Brain Injury: Biomarker Project

The goal of this study is to better understand that which contributes to the long-term recovery of people who have sustained a traumatic brain injury. To better understand an individual’s recovery following a head-injury, we will measure and examine the chemicals released in the brain and blood following the injury. …

18-99 years
All
Phase N/A

Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project

TRACK-TBI EPI is an observational study of the TRACK-TBI longitudinal cohort. Subjects will be contacted 2-5 years after their index TBI for consent to a phone interview. Those who screen positive for possible post-traumatic epilepsy will be invited for an in person visit, which will involve a clinical evaluation by …

18-90 years
All
Phase N/A

Simple Mask Modification for Increased Protection during COVID-19

While there is a limited supply of personal protective equipment (PPE) during the Covid-19 pandemic, there is a larger availability of surgical masks compared to N95 masks. If a surgical mask could be modified to eradicate the leaks throughout the circumference of the mask, it may be able to filter …

18-99 years
All
Phase N/A

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