Found 706 clinical trials
Pragmatic Clinical Trial Comparing Smoking Cessation Interventions among Underserved Patients who are referred for Lung Cancer Screening
Low-dose computed tomography (LDCT) screening reduces mortality among current and former smokers at high risk for lung cancer, and is widely recommended by national guidelines. LDCT also increases access to care and thus provides an opportunity to deliver smoking cessation interventions to current smokers in conjunction with this screening. As …
Identification of neoantigen-specific T cell responses in cancer patients within the Penn Medicine BioBank
You are being asked to participate in this research investigation because you have expressed an interest in participating in a study to better understand how the immune cells of the body recognize and fight cancer.
Efficacy of DE-MRI-Guided Fibrosis Ablation vs. Conventional Catheter Ablation of Atrial Fibrillation: The DECAAF II Study
You are being asked to participate in this study because you have atrial fibrillation and are planning to undergo an ablation procedure to treat this heart rhythm irregularity.
SMaRT Blood: Single-unit versus Multiple-unit pRBC Transfusion in non-acute postpartum anemia
Blood transfusion is often recommended for women who have anemia (low blood counts) after delivering a baby. Currently, many doctors give 2 units, or packets, of blood because they expect that everyone will need 2. However, it may be better to only give 1 unit at a time to raise …
“Real World” Administration of Zepatier (Grazoprevir plus Elbasvir in Chronic Hemodialysis Patients with Hepatitis C Infection. Strategies for Identification of Candidate Hemodialysis Patients, Obtainment of Insurance Approval, Treatment Guidelines, and Laboratory and Clinical Monitoring During Therapy Directed to Nephrologists
The purpose of this study is to learn how to dialysis doctors can treat dialysis patients infected with Hepatitis C themselves. Hepatitis C infection is common in hemodialysis patients. There are new medications, such as Zepatier, which can cure hepatitis C in > 95% of patients. Zepatier is particularly good …
Randomized Trial of Stepped Palliative Care versus Early Integrated Palliative Care in Patients with Advanced Lung Cancer
We are inviting you to take part in a research study. Research is a way of gaining new knowledge. A person who participates in a research study is called a “participant.” This research study is evaluating ways to provide palliative care to patients who have recently been diagnosed with lung …
PERI-PROCEDURAL TRANSMURAL ELECTROPHYSIOLOGICAL IMAGING OF SCAR-RELATED VENTRICULAR TACHYCARDIA
Ventricular tachycardia (VT) is a serious condition that results in your heart beating much faster than its usual rate. Catheter ablation, which is burning the irregular electrical activity in the heart muscle through wires, is one of the methods that has been used in the treatment of VT. In order …
A pilot randomized control trial to determine the feasibility of a hypnosis intervention for the treatment of bladder pain syndrome/interstitial cystitis.
The purpose of this research study is determine the feasibility of a hypnosis intervention to women with bladder pain syndrome. We also plan to assess the effect of hypnotic words and suggestions on brain function. Hypnotherapy has been studied in other chronic pain conditions and has been shown to be …
Effects of mu-opiate receptor engagement on microbial translocation and residual immune activation in HIV-infected, ART suppressed opioid use disorder patients initiating medication-assisted treatment
The purpose of this research study is to examine the impact of medications (methadone, buprenorphine, or extended-release naltrexone) used to treat opioid use disorder on the immune system — the body’s ability to fight infection. The study will try to find out how these opioid treatment medications affect immune function. …
A Randomized Controlled Trial of Women Involved in Supporting Health (WISH), a Peer-Led Intervention to Improve Postpartum Retention in HIV Care
The purpose of the study is to learn more about programs that can improve the health and wellbeing of mothers and their babies during the period after delivery. Women living with HIV experience diverse health problems in the period directly after delivery. These problems are related to poor medical visit …
