Found 706 clinical trials
Investigating Potential of Personalized Biomarkers in Redefining Treatment Response in Patients with Glioblastoma using Multiparametric MRI and Liquid Biopsy
This study aims to investigate 30 patients with a diagnosis of Glioblastoma to develop a decision support system by incorporating advanced MR imaging, liquid biopsy, and MGMT promoter status to determine with higher accuracy whether tumor changes are true progression or pseudo progression. Analysis of these results will hopefully have …
Testing Novel Pharmacogenetic and Adherence Optimization Treatments to Improve the Effectiveness of Smoking Cessation Treatments for Smokers with HIV
The research study is being conducted to examine the effects of personalized smoking cessation medication treatment in order to help people with HIV/AIDS to quit smoking. During the study, participants will take either varenicline (brand name Chantix®) or use the nicotine patch, and they will receive smoking cessation therapy with …
A Novel Method for Glutamate Imaging
This research study will test the performance of new magnetic resonance imaging and spectroscopy techniques at 7.0 Tesla. These new methods have already been tested in model systems and need to be tried on human subjects prior to use in patient populations. The study is expected to continue for five …
Development and Maintenance of Software for MR Spectroscopic Imaging
This research study will test the performance of new magnetic resonance imaging techniques at 7.0 Tesla. These new methods have already been tested in model systems and need to be tried on human subjects prior to their applications in determining important substances in the whole brain. . This study is …
Changes in muscle creatine at 7.0 Tesla
The purpose of this study is to obtain pictures of the skeletal muscle of subjects before and after exercise using high resolution Magnetic Resonance Imaging (MRI) methods. The MRI will use magnets to take pictures of your skeletal muscle that will allow us to see small details in the muscle …
Testing of Magnetic Resonance Methods at 7.0 Tesla
The research study will test the performance of new magnetic resonance imaging and spectroscopy techniques at 7.0 Tesla. These new methods have already been tested in model systems and need to be tried on human subjects prior to use in patient population.
Epidemiological study to characterize the prevalence and distribution of lipoprotein (a) levels among patients with established cardiovascular disease.
The purpose of this study is to collect information about the blood level of a specific marker (lipoprotein (a)). Similar to other blood lipids, such as the "bad cholesterol", lipoprotein (a) levels were found to be associated with the risk of hardening of the arteries, known as atherosclerosis, which leads …
Effects of Dietary Interventions on Health and Well-Being
Do you feel out of control around junk foods?The purpose of this study is to examine how different dietary interventions affect health, mood, and concentration in individuals who report feeling out of control around junk foods. Possible benefits of the study may be helping you change your diet and/or lose weight.
Neural correlates of cognitive fatigue and bright light treatments in older adults
The purpose of this study is to learn more about how cognitive fatigue affects performance and how exposure to light may influence this effect
Multicenter Study to Evaluate the Impact of Evolocumab on Major Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke
The purpose of this research study is to assess whether lowering of your cholesterol blood level can reduce your risk for major cardiovascular events (for example, heart attack or stroke) when evolocumab is taken in addition to your current medical therapy as directed by your doctor, which may include a …
