Found 706 clinical trials
Genomic Epigenetic Proteomic Metabolomic and Immunologic Characterization of Metastatic Neuroendocrine Tumors Surviving Transarterial Embolotherapy
mNET is commonly treated with TACE or TACE. mNET cells can survive TACE or TARE ischemic conditions. In this study, we will biopsy mNETs being treated with TACE or TARE prior to treatment, after treatment, and again at recurrence to characterize the metabolic, immunologic, and genetic profile of the cells …
Effects of Insomnia Treatment on Metabolism in Patients with Depression
800x600 Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Are you currently depressed and have trouble sleeping? Are you between the ages of 21 and 60? You may be eligible for one of our current research studies:Cognitive behavioral therapy for insomnia (CBT-I) has been the ‘gold standard’ for the …
IMAGING OF IN VIVO SIGMA-2 RECEPTOR EXPRESSION WITH [18F]ISO-1 POSITRON EMISSION TOMOGRAPHY (PET/CT) IN METASTATIC BREAST CANCER
Patients with metastatic breast cancer, that is biopsy proven or clinically documented by standard imaging (e.g. CT, MRI, Bone Scan, Ultrasound, FDG PET/CT), may be eligible for this study. Patients may participate in this study, if they are at least 18 years of age. We anticipate enrolling up to 30 …
Chronic insomnia and CSF markers of dementia
The purpose of this study is to identify the relationship between chronic sleep disturbance and chemicals in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.
Mechanisms for Individual Differences in Hypertension in Obstructive Sleep Apnea
The purpose of this study is to compare the response to PAP treatment of patients with Obstructive Sleep Apnea (OSA) who have normal blood pressure to those with treated (that is taking medication or on a special diet) high blood pressure.
Evaluating the microbiota diversity and bile acid composition of patients with primary sclerosing cholangitis.
You are invited to participate in a research study that will look at the impact of primary sclerosing cholangitis on the gut.
A Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Magnesium in Patients with Primary Biliary Cholangitis
You are invited to take part in this research project. This is because you have a disease of the liver called Primary Biliary Cholangitis (sometimes referred to as Primary Biliary Cirrhosis). The purpose this study is to test a new treatment for this condition called Saroglitazar magnesium.
UPCC 09517: Phase II study of Pembrolizumab and Itacitinib (INCB039110) for First Line Treatment of Metastatic Non-Small Cell Lung Cancer Expressing PD-L1
The main purpose of this study is to examine the efficacy of adding itacitinib (also known as INCB039110) to pembrolizumab in patients with previously untreated metastatic non-small cell lung cancer.
Daily Liraglutide for Nicotine Dependence
We are currently recruiting smokers who are interested in quitting for a research study that involves taking a medication called liraglutide. Liraglutide is also marketed under the name Saxenda®.Liraglutide is an injectable medicine that may help some adults with who are overweight or obese lose weight and keep the weight …
Investigation of the Effect of Branched Chain Amino Acids on Fat-Induced Insulin Resistance in Healthy Adults.
Elevations in plasma levels of branched chain amino acids (BCAAs, comprising leucine, valine, and isoleucine), a large component of protein, are strongly associated with insulin resistance and type 2 diabetes, but mechanisms for this relationship are unclear. This protocol will determine whether excess BCAAs worsen free fatty acid-induced insulin resistance. …
