Found 706 clinical trials
World-wide Randomization Antibiotic Envelope Infection Prevention Trial (WRAP-IT)
This study is a single-blinded,randomized,prospective, multi-center clinical trial. The study will evaluate the ability of the TYRX absorable Antibacterial Envelope to reduce major cardiovascular implantable electronic device (CIED) infections. Patients undergoing CIED generator replacement, upgrade, revision or new biventricular defibrillator system will be randomized to receive the TYRX envelope or …
FIT-PLESE: A study for overweight women with unexplained infertility, seeking pregnancy report Trial 3
FIT-PLESE is a research study to find out the effects of lifestyle modification in obese women with unexplained infertility. Eligible participants will be randomized to either an Intensive Lifestyle Modification Program or a Standard Physical Activity Program for 16 weeks, followed by fertility treatment with ovarian stimulation and intrauterine insemination.
A Six-Week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in Subjects with Obstructive Sleep Apnea (OSA)
Medication trial for the treatment of excessive sleepiness in adult subjects with treated or untreated obstructive sleep apnea (OSA).
A Natural History Study of Charcot-Marie-Tooth
This is a longitudinal study of individuals with CMT looking at the natural history of the disease to see how it changes over time. Participants are invited back on a yearly basis to determine how the changes are occurring.
Variability in Response to Non-steroidal Anti-inflammatory Drugs
The purpose of this research study is to measure the difference in response to non-steroidal anti-inflammatory drugs (NSAIDs) among people. We will also study what factors, like age, sex, or genetic background, cause these differences.
Pregabalin (Lyrica) in the Management of Oral Mucositis Pain in Head/Neck Chemoradiation Therapy Patients
Double-blind, randomized, single-center pilot study to assess the effectiveness of pregabalin (Lyrica) in the management of mucositis pain in head and neck cancer.
Startle Response in Women with Premenstrual Mood Disorders
This study examines stress response in women with premenstrual mood changes. For this study, you will be asked to fill out forms about your physical and mental health, have blood and saliva samples taken, and undergo a test that will measure your stress responses. This is a long-term study, consisting …
Normal Donor Human Bone Marrow Donation for Research
We are looking for healthy volunteers to donate bone marrow for research purposes. The Stem Cell & Xenograft Core provides bone marrow to laboratories on Penn’s campus researching leukemia and other blood disorders
The Neural Basis for Frontotemporal Degeneration
The purpose of this research study is to develop a better understanding of the genetic causes for frontotemporal degeneration (FTD), as well as Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA). These conditions include difficulty with language and speaking, organization and planning, memory, and/or a behavior or personality change. …
Conceptual Processing in Alzheimer’s Disease
The purpose of this study is to evaluate memory, language and cognitive difficulties in patients with AD. AD is a neurological disease where a specific part of the brain is not functioning well. A clinical diagnosis of AD needs to be confirmed in all participants prior to participation in the …
