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Found 706 clinical trials

Serenity Study: Lowering High Blood Pressure with Stress Management Techniques

The Serenity Study is a voluntary research study that will investigate different approaches to stress management in order to help lower blood pressure. You may be eligible to participate if you: have blood pressure in the pre-hypertensive range (systolic BP 120-139 or diastolic BP 80-89), are a healthy adult between …

21-70 years
All

EFICACIA Y SEGURIDAD DE UN MEDICAMENTO INYECTABLE UNA VEZ A LA SEMANA EN PARTICIPANTES CON SOBREPESO U OBESIDAD. (REDEFINIR 1)

Este es un estudio de prueba de concepto multicéntrico, aleatorizado, doble ciego, controlado con placebo, de 2 brazos, de grupos paralelos. El objetivo principal de este estudio es evaluar el efecto de dupilumab en el alivio de los síntomas clínicos de la EoE y la reducción de la inflamación esofágica …

1-99 years
All
Phase 3

FES PET/CT in Endocrine Refractory Breast Cancer

Patients with recurrent or metastatic ER+ breast cancer, who have failed prior endocrine therapy may be eligible for this study.  Patients may participate in this study, if they are at least 18 years of age, most participants will be receiving care at the clinical practices of the University of Pennsylvania. …

18-99 years
Female
Phase 3

Radiation Oncology Registry

You are being asked to participate in the Radiation Oncology Registry. Participation in this study requires no additional obligations on your part; your participation means you are granting permission for your doctors to extract information from your medical chart and use this data for research purposes. Should any findings from …

18-99 years
All
Phase N/A

Mild Hypofractionation using Proton Therapy or IMRT for Low- and Intermediate-Risk Prostate Cancer

This is a study to first establish feasibility of the study and then to register the treatment data of adult patients with a diagnosis of low or intermediate risk of prostate cancer presenting for definitive radiation treatment with either proton radiotherapy or IMRT. We propose to employ a hypofractionated strategy …

99 years and younger
All
Phase N/A

Randomized, Double Blind, Placebo-Controlled Trial of the Safety and Efficacy of HORIZANT® (Gabapentin Enacarbil) Extended-Release Tablets for the Treatment of Alcohol Use Disorder

Alternating phone and in-clinic visits for medical management (MM), laboratory tests, and physical exams, to assess drug compliance, to complete additional questionnaires, and to provide counseling (via “Take Control” videos) over 29 weeks.

21 years and older
All
Phase 2

The Effect of Potassium Nitrate [KNO3] on Exercise Capacity in Heart Failure Patients.

This study will test whether Potassium Nitrate (KNO3) will improve how people with HFpEF [Diastolic Heart Failure] can exercise. In HFpEF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to becoming tired and short …

18-90 years
All
Phase 2

METAMORPH

This is a cohort study of women with suspected or confirmed recurrent breast cancer, with accessible tumor by standard clinical biopsy, prior to starting a new therapy for recurrent metastatic disease. Study participants will be ascertained from the population of all persons greater than eighteen years of age receiving care …

99 years and younger
All
Phase N/A

North American Registry for Care and Research in MS - NARCRMS

NARCRMS is a national database that collects patient and physician-based information on MS and will bring together information and data collected in multiple registries and databases across the U.S. and Canada. We expect that data collected consistently over long periods of time, when carefully studied, will 1) produce new clues …

18-50 years
All

Quality Improvement Assessment for Patient-Centered Community Health Worker Intervention

The purpose of the IMPaCT Transitions program is to help low-income general medicine patients who have been cared for at the Hospital of the University of Pennsylvania or Presbyterian Hospital with the transition from hospital to a primary care clinic. The purpose of IMPaCT Home is to help low-SES patients …

18-99 years
All
Phase N/A

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