Liver Disease Clinical Trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 33 clinical trials
A Phase 2B Randomized Double-Blind Placebo-Controlled Study Evaluating the Safety and Efficacy of BMS-986036 (PEG-FGF21) in Adults with Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis

A phase 2B, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of BMS-986036 in subjects with NASH and F3 fibrosis. The treatment period is 48 weeks, with drug administered as a once-weekly injection. There is also a follow-up period to assess long-term bone mineral density and immunogenicity. Target population …

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  • 19 Feb, 2024
  • 1 location
A Phase 2 Randomized Controlled Dose-titration Open-Label Study Evaluating the Safety and Efficacy of BIV201 in Addition to Standard of Care Compared to Standard of Care to Reduce the Recurrence of Ascites and Complications in Patients with Refractory Ascites Secondary to Decompensated Liver Cirrhosis

TBD

  • 0 views
  • 19 Feb, 2024
  • 1 location
CARDIOVASCULAR PULMONARY AND RENAL PHENOTYPES IN COVID-19 SURVIVORS

In this study, the Investigator at the University of Pennsylvania will assess organ-specific biomarker profiles (proteins and metabolites), in order to better understand biologic processes, the interplay between the heart and extracardiac organs, and their role in human disease, with an emphasis on cardiovascular disease. The study will specifically focus …

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  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Safety and Efficacy of Image Guided Surgery using Indocyanine Green for Intramolecular Imaging of Solid Tumors Compared to Standard of Care (TumorGlow) (PRIME)

Indocyanine Green (ICG) is an FDA approved, water-soluble tricarbocyanine dye routinely used in clinical settings for measuring cardiac output, liver function, and retinal angiography and has been in use for over 50 years. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment.

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  • 19 Feb, 2024
  • 1 location
A Phase 2B Randomized Double-Blind Placebo-Controlled Study Evaluating the Safety and Efficacy of BMS-986036 (PEG-FGF21) in Adults with Nonalcoholic Steatohepatitis (NASH) and Compensated Liver Cirrhosis

A phase 2B, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of BMS-986036 in subjects with NASH and compensated cirrhosis. The treatment period is 48 weeks, with drug administered as a once-weekly injection. There is also a follow-up period to assess long-term bone mineral density and immunogenicity. Target population …

  • 0 views
  • 19 Feb, 2024
  • 1 location
TARGET-PBC: A 5-year Longitudinal Observational Study of Patients with Primary Biliary Cholangitis

You are being asked to be in this research study because you have PBC (primary biliary cholangitis) which is an uncommon chronic cholestatic liver disease characterized by progressive inflammation and destruction of the interlobular bile ducts, ultimately leading to the development of biliary cirrhosis.

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  • 19 Feb, 2024
  • 1 location
A Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Magnesium in Patients with Primary Biliary Cholangitis

You are invited to take part in this research project. This is because you have a disease of the liver called Primary Biliary Cholangitis (sometimes referred to as Primary Biliary Cirrhosis). The purpose this study is to test a new treatment for this condition called Saroglitazar magnesium.

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  • 19 Feb, 2024
  • 1 location
Development of a reliable means for functional assessment of liver performance after Fontan operation: dual cholate clearance assay

Furthermore, by the time laboratory abnormalities are found in the blood, liver disease may be advanced and it could be too late. A novel test called HepQuant® is an assay used to measure liver function in other types of liver disease and has been shown to predict liver-related complications in …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Prevention of Mortality with Long-Term Administration of Human Albumin in Subjects with Decompensated Cirrhosis and Ascites

This study is designed to evaluate the effects of Albutein 20% infusion on long-term survival (1-year transplant-free) in liver cirrhosis compared to the Standard Medical Treatment (SMT).

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  • 19 Feb, 2024
  • 1 location
UPCC 31218: A prospective multicentre randomised controlled study evaluating SIR-Spheres Y-90 resin microspheres preceding standard cisplatin-gemcitabine (CIS-GEM) chemotherapy versus CIS-GEM chemotherapy alone as first-line treatment of patients with unresectable intrahepatic CholangioCArcinoma (SIRCCA)

The main purpose of this research study is to find out whether Selective Internal Radiation Therapy (SIRT) preceding a standard chemotherapy treatment can improve survival in patients with cholangiocarcinoma in the liver, compared to chemotherapy alone.

  • 0 views
  • 19 Feb, 2024
  • 1 location