Tobacco Use Disorder Clinical Trials
A listing of Tobacco Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 32 clinical trials
Brain and behavioral effect of tobacco labeling and packaging on adolescents at risk for nicotine dependence
The University of Pennsylvania is conducting a study of brain responses to graphic health warnings. The study includes receiving cell phone messages for 4 weeks and two functional Magnetic Resonance Imaging (fMRI) scans of the brain. These scans are non-invasive and do not use X-ray. To be eligible to participate, …
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- 19 Feb, 2024
- 1 location
Daily Liraglutide for Nicotine Dependence
We are currently recruiting smokers who are interested in quitting for a research study that involves taking a medication called liraglutide. Liraglutide is also marketed under the name Saxenda®.Liraglutide is an injectable medicine that may help some adults with who are overweight or obese lose weight and keep the weight …
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- 19 Feb, 2024
- 1 location
The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addiction
The effects of the NMR on quitting success are greater than the effects of other clinical measures (e.g., the severity of nicotine dependence), such that NMR is the strongest genetically-informed biomarker of smoking cessation. Differences in brain receptor levels secondary to differing durations of nicotine present in the brains of …
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- 19 Feb, 2024
- 1 location
Targeting the Cholinergic Pathway in HIV-associated Inflammation and Cognitive Dysfunction
Although anti-retroviral therapy (ART) enhances life expectancy and overall quality of life (QoL), HIV-infected individuals are increasingly vulnerable to non-AIDS-related diseases including HIV-associated neurocognitive disorders (HAND). Inflammation is a primary mechanism in the pathogenesis of HAND and tobacco use may further exacerbate inflammation. Conversely, nicotine alone has anti-inflammatory effects suggesting …
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- 19 Feb, 2024
- 1 location
Measurement of Pulmonary Inflammation Using F-NOS Positron Emission Tomography (PET/CT) in E-cigarette Users
This is a 1 – 2 month study examining the extent of lung inflammation between e-cigarette smokers, cigarette smokers, and non-smokers using a new radio tracer, FNOS. FNOS is an experimental radio tracer used to look for inflammation in different parts of the body. The tracer that we will be …
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- 19 Feb, 2024
- 1 location
