Barrett's Esophagus Clinical Trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 349 clinical trials
Dose Escalation Study of Intravenous PRX004 in Subjects with Amyloid Transthyretin (ATTR) Amyloidosis

 The purpose of this study is to: • Determine the highest dose of PRX004 up to a set maximum that can safely be given without unacceptable (intolerable) side effects to subjects with hereditary ATTR amyloidosis. • Determine what dose or doses of PRX004 should be used in future research studies on subjects …

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  • 19 Feb, 2024
  • 1 location
Extreme Phenotypes and Obstructive Sleep Apnea

Obstructive sleep apnea typically causes daytime sleepiness and fragmented (broken up) sleep. Obesity is thought to be the most important risk factor for sleep apnea, yet we currently do not understand how obesity increases the likelihood of having sleep apnea.

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  • 19 Feb, 2024
  • 1 location
Autism Spectrum Program of Excellence

Individuals 3 years old or older with a diagnosis (or suspected diagnosis) of autism spectrum disorder without intellectual disability may be eligible to participate. We are also recruiting individuals with a deletion or mutation in the NRXN1 gene.

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  • 19 Feb, 2024
  • 1 location
Network Control TMS fMRI

We are also interested in using TMS during a working memory test to see how it affects task performance. TMS involves a procedure during which your brain will be noninvasively (i.e. from the scalp) stimulated by magnetic pulses and MRI scans are used to take pictures of your brain. In …

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  • 19 Feb, 2024
  • 1 location
Recovery-Oriented Cognitive Therapy for Families

The purpose of this study is to evaluate the therapeutic benefit for participants receiving Recovery-Oriented Cognitive Therapy (CT-R) for families- a cognitive therapy based group for family members of individuals in the early stages of psychosis. A CT-R based intervention has shown to be effective for individuals with psychosis, offers …

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  • 19 Feb, 2024
  • 1 location
A Phase 1/2 Randomized Double-Blind Placebo-Controlled Combined Single and Multiple Ascending Dose Study Evaluating the Safety Tolerability and Biological Activity of MRT5005 (COhCFTR mRNA/ICE LNP) Administered by Nebulization to Adult Subjects with Cystic Fibrosis

This research study is being done to study a new way to possibly treat cystic fibrosis lung disease. The investigational drug to be tested in the present study is known by its code name MRT5005. MRT5005 consists of very small particles containing messenger ribonucleic acid (mRNA), which has the genetic …

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  • 19 Feb, 2024
  • 1 location
An International, Open Label, Randomised Controlled Trial Comparing Rituximab with Azathioprine as Maintenance Therapy in Relapsing ANCA-Associated Vasculitis  

Vasculitis can affect almost any part of the human body. Vasculitis can be very serious if left untreated. This study will investigate whether repeating rituximab really works well in stopping vasculitis returning and is better than the drugs usually used for this purpose-azathioprine or methotrexate.

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  • 04 Dec, 2025
  • 1 location
Organ Specific Blood Sample Collection for Advancing Research in Mechanisms of Human Disease

The study will specifically focus on the role of the liver, kidneys, lungs, and skeletal muscle, and their interactions with the heart as determinants of cardiovascular disease. This will be achieved by drawing arterial and venous blood from key organs among patients undergoing clinically-indicated cardiac catheterization or electrophysiological studies, who, …

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  • 19 Feb, 2024
  • 1 location
Evaluation of the GORE TAG Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta

Subjects must have such an aortic lesion, which requires surgical repair, and must meet specific anatomical and disease conditions to be eligible for the study. If eligible, subjects will undergo surgical repair of the descending thoracic aorta or aortic arch, as appropriate, using the study device.

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  • 19 Feb, 2024
  • 1 location
AN UN-BLINDED INTRA-PATIENT COMPARISON OF TRANSBRONCHIAL FORCEPS BIOPSY AND CRYOBIOPSY FOR PERIPHERAL PULMONARY LESIONS

All patients will undergo both biopsy types and the success of providing a diagnosis will be compared.

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  • 19 Feb, 2024
  • 1 location