Barrett's Esophagus Clinical Trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 349 clinical trials
Chronic insomnia and CSF markers of dementia
The purpose of this study is to identify the relationship between chronic sleep disturbance and chemicals in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.
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- 19 Feb, 2024
- 1 location
SIMCAP (Surgery in Metastatic Carcinoma of Prostate): Phase 2.5 multi-institution randomized prospective clinical trial evaluating the impact of cytoreductive radical prostatectomy combined with best systemic therapy on oncologic and quality of life outcomes in men with newly diagnosed metastatic prostate cancer
Subjects will then begin BST. Tumor samples will be collected for research purposes. During the study, there will be exams, tests, and procedures. Subjects must follow-up every three months to report symptoms, health problems, new medications, receive physical examination, and blood tests.
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- 19 Feb, 2024
- 1 location
A Randomized Trial of Pessary in Singleton Pregnancies with a Short Cervix
Although vaginal progesterone and cerclage have been shown to reduce the risk, results have not been uniformly positive, and a low-cost, simple and effective method would be of great value, especially globally. The cervical pessary is such a treatment. This randomized trial will evaluate whether a cervical pessary can reduce …
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- 19 Feb, 2024
- 1 location
A Better FIT! Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment
Participants who do not lose weight with lifestyle modification alone also will be prescribed an FDA-approved weight loss medication (phentermine) or placebo.
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- 21 Nov, 2025
- 1 location
Phase 2 Trial of AGEN2034 (anti-PD-1) as a Monotherapy of Combination Therapy with AGEN1884 (anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer (Second Line) - RaPiDS
Collection of stored tumor specimen from previous biopsy to test for PD-L1 expression later. If stored tumor specimen is not available, a fresh biopsy will be required.
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- 19 Feb, 2024
- 1 location
A multi-center double-blind placebo-controlled Phase 4 study in patients with pulmonary arterial hypertension to assess the effect of selexipag on daily life physical activity and patients self-reported symptoms and their impacts
The purpose is to identify the effect of selexipag on daily life physical activity assessed by a wearable device in patients with PAH (WHO Group 1). Approximately 100 patients will be enrolled in the study at 45 sites in 12 countries.
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- 19 Feb, 2024
- 1 location
IMAGING OF IN VIVO SIGMA-2 RECEPTOR EXPRESSION WITH [18F]ISO-1 POSITRON EMISSION TOMOGRAPHY (PET/CT) IN METASTATIC BREAST CANCER
This is an observational study in that [18F]ISO-1 PET/CT will not be used to direct treatment decisions. While patients and referring physicians will not be blinded to the [18F]ISO-1 PET/CT results, treatment decisions are made by the treating physicians based upon clinical criteria.
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- 19 Feb, 2024
- 1 location
Multicenter randomized double-blind parallel-group add-on superiority study to compare the efficacy and safety of ponesimod to placebo in subjects with active relapsing multiple sclerosis who are treated with dimethyl fumarate (Tecfidera )
This is a study to find out whether patients with active forms of Relapsing Multiple Sclerosis (RMS) who are treated with dimethyl fumarate (Tecfidera®) can be treated better by the addition of ponesimod (study drug). The purpose is also to evaluate the effect on disability and the safety of these …
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- 19 Feb, 2024
- 1 location
Propranolol Rescue of Prolonged Labor
They must meet one of the following study criteria for prolonged labor: 1) not in active labor (defined as cervical dilation greater than or equal to 6cm) after 12 hours with ruptured membranes and receiving oxytocin, or 2) in active labor (defined as cervical dilation greater than or equal to …
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- 19 Feb, 2024
- 1 location
Trial of ASP-1929 Photoimmunotherapy Versus Physician's Choice Standard of Care for the Treatment of Locoregional Recurrent Head and Neck Squamous Cell Carcinoma
This is a Phase 3, randomized, double-arm, open-label trial of ASP-1929 photoimmunotherapy (ASP-1929 PIT) versus physician's choice standard of care (SOC) for the treatment of locoregional, recurrent head and neck squamous cell carcinoma (HNSCC) in patients who have failed or progressed on or after at least two lines of therapy, …
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- 19 Feb, 2024
- 1 location