Mitral Valve Regurgitation Clinical Trials

A listing of Mitral Valve Regurgitation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 15 clinical trials
Featured trial
PD GPI MRFGUS

To demonstrate ExAblate procedure is safe and works.There is evidence in medical literature showing that by ablating a particular cluster of cells in the brain, dyskinesia (abnormal movements)&motor symptoms of PD may improve. ExAblate can be used to perform ablation more precisely in minimally invasive fashion. In this study we …

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  • 19 Feb, 2024
  • 1 location
Pilot study for functional and structural MR Imaging of Endobroncial valve recipients using hyperpoloarized XENON-129

We propose to use gas Magnetic Resonance Imaging (MRI) using the inhaled contrast agent, hyperpolarized (HP) xenon-129, to study the lungs of 20 volunteers who have received or will receive endobronchial valve (EBV) therapy as a treatment for COPD. Since its recent FDA approval, investigators have yet to explicitly assess …

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  • 19 Feb, 2024
  • 1 location
FOLLOW-UP VESSEL WALL MR IMAGING TO EXPLORE SEX-DIFFERENCES OF INTRACRANIAL ARTERIAL WALL CHANGES AND INTRACRANIAL ATHEROSCLEROTIC PLAQUE TREATMENT EFFICACY

Yet surprisingly, the development and progression of ICAD has not been explored in women despite the intimate association with stroke. High-resolution vessel wall MR imaging (VWI) permits visualization of vessel wall changes and may potentially serve as a noninvasive screening test for populations of women for early ICAD detection.

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  • 19 Feb, 2024
  • 1 location
Cancer detection rate of Abbreviated (Fast) Breast MRI (AB-MR) after negative Digitial Breast Tomosynthesis in Women status post Conservation Therapy (BCT)

Women treated for primary breast cancer who undergo breast conservation therapy face an increased risk of developing a second breast cancer in the ipsilateral and the contralateral breast. Although mammographic screening is recommended annually, the sensitivity of mammography is limited in these patients due to the post treatment changes from …

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  • 19 Feb, 2024
  • 1 location
Investigating Potential of Personalized Biomarkers in Redefining Treatment Response in Patients with Glioblastoma using Multiparametric MRI and Liquid Biopsy

This study aims to investigate 30 patients with a diagnosis of Glioblastoma to develop a decision support system by incorporating advanced MR imaging, liquid biopsy, and MGMT promoter status to determine with higher accuracy whether tumor changes are true progression or pseudo progression.

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  • 19 Feb, 2024
  • 1 location
Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for High Surgical Risk Patients

This is a study of the MitraClip, percutaneous mitral valve repair system in patients with moderate to severe to severe functional mitral regurgitation who need surgical repair but are deemed not appropriate for surgery. Patients will be randomized in a 1:1 fashion to treatment with the Mitra Clip system or …

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  • 19 Feb, 2024
  • 1 location
Transcranial Magnetic Stimulation Exploration of Motor Cortex Functional Anatomy

The purpose of the proposed study is to explore the nature of the codes that are present in the primary motor cortex. All complex actions involves the contraction of multiple muscles, the timing and intensity of which is precisely modulated. The traditional view of this process is that an abstract …

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  • 19 Feb, 2024
  • 1 location
Partner 3 Biscuspid Registry: A Prospective Randomized Controlled Mult-Center Study to Establish the safety and Effectiveness of Sapien 3 Transcatheter Heart Valve in low risk patients who have severe calcific aortic stenosis requiring aortic valve replacement

TBD

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  • 19 Feb, 2024
  • 1 location
Comparing the effects of Oral Contraceptive Pills versus Metformin in the medical management of overweight/obese women with Polycystic Ovary Syndrome

OCPs increase the risk of MetS specifically by producing an atherogenic lipoprotein phenotype, increasing blood pressure and/ or body weight while metformin modestly decreases MetS risk by decreasing body weight and improving lipid phenotype. The combination of OCP and metformin (OCP, through lowering androgens, and metformin, through improvement in insulin …

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  • 19 Feb, 2024
  • 1 location
Development and Maintenance of Software for MR Spectroscopic Imaging

This research study will test the performance of new magnetic resonance imaging techniques at 7.0 Tesla. These new methods have already been tested in model systems and need to be tried on human subjects prior to their applications in determining important substances in the whole brain. . This study is …

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  • 19 Feb, 2024
  • 1 location