Kidney Transplantation Clinical Trials

Randomized Controlled Trial to Evaluate the Effect of Lost Wage Reimbursement to Potential Kidney Donors on Living Donation Rates

This study is being done to learn if offering to reimburse kidney donors for wages they would lose by being off work during the donation evaluation and surgery process increases the likelihood of the kidney transplant recipient to receive a living kidney transplant within one year. Eligible subjects will be …

None

None

None

None

HOPE in Action Prospective Multicenter Clinical Trial of HIV+ Deceased Donor Kidney Transplants for HIV+ Recipients

Use of an HIV+ deceased donor could increase the risk of death, transplant-related or HIV-related complications; alternatively with effective antiretroviral treatment and careful HIV+ donor selection, these risks may be comparable to kidney transplant using an HIV-negative donor. We hypothesize that receiving a kidney transplant from an HIV+ donor will …

A Phase III Randomized Double-Blind Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of MK-8228 (Letermovir) Versus Valganciclovir for the Prevention of Human Cytomegalovirus (CMV) Disease in Adult Kidney Transplant Recipients

The purpose of the study is to compare letermovir to valganciclovir in preventing CMV disease in patients who have received a kidney transplant and are considered to be at high-risk for CMV disease after their transplant. The main study intervention is taking letermovir (or placebo for letermovir) plus valanciclovir (or …

A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-Negative kidney recipients

Patients who are on the kidney transplant waitlist and do not have hepatitis C will be asked to participate. 

A phase IV prospective randomized open-label single-center study of pulse wave velocity evaluation tacrolimus time in therapeutic range and co-efficient of tacrolimus variation of African American kidney transplant recipients receiving immediate release tacrolimus capsules (IR-Tac) or extended release tacrolimus tablets (LCPT)

The secondary purpose is to look at the effectiveness and safety of extended release tacrolimus tablets administered once-daily compared to generic tacrolimus capsules administered twice-daily after kidney transplantation.