Epilepsy Clinical Trials

Evaluation of the 24/7 EEG SubQ System for Ultra Long-Term Recording of Patients with Temporal Lobe Epilepsy

see protocol section 2.

An Open-Label Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Buccal Soluble Film (DBSF) in Adult Subjects With Epilepsy.

You are being asked to be in this study because you have epilepsy and you take epilepsy medication. Aquestive Therapeutics (the study Sponsor) has begun a research study of an investigational drug called Diazepam Buccal Soluble Film or DBSF as a possible treatment for patients with epilepsy.

Padsevonil as adjunctive treatment of focal-onset seizures

You are being asked to participate in this clinical research study because you have epilepsy associated with focal onset seizures (or sometimes called partial seizures), and your seizures are not well controlled with your current treatment.

A Randomized Double-blind Placebo-controlled Multicenter Study to Evaluate the Efficacy and Safety of Cenobamate Adjunctive Therapy in Subjects with Primary Generalized Tonic-Clonic Seizures

see synopsis

Study of Carisbamate in Adult and Pediatric Subjects with Lennox-Gastaut Syndrome

The purpose of this study is to learn more about the use of carisbamate (the Study Drug) for the treatment of LGS in children and adults. The Study Drug has not yet been approved by the FDA - it is an experimental treatment. The Study Drug belongs to the anti-convulsant …

An Exploratory Case-Control Study of Genetic and Clinical Factors For Serious Cutaneous Reactions Among Users of Eslicarbazepine Acetate With New Medications taken for atleast 3 months prior to the study

Eslicarbazepine acetate (Aptiom®) is an antiepileptic drug (AED) approved in the United States (US) as adjunctive therapy for the treatment of partial-onset seizures in adults .Prior research has shown that seizure medicines like carbamazepine (Tegretol®) and oxcarbazepine (Trileptal®, Oxtellar®) are more likely to cause severe drug related skin reactions in …

Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project

Subjects will be contacted 2-5 years after their index TBI for consent to a phone interview. Those who screen positive for possible post-traumatic epilepsy will be invited for an in person visit, which will involve a clinical evaluation by an epileptologist, a blood draw, MRI, and EEG.

Open-label Extension Study to Evaluate the Long-term Safety of Cenobamate Adjunctive Therapy in Subjects with Primary Generalized Tonic- Clonic Seizures

The research study is being conducted to evaluate the long-term safety and tolerability of cenobamate for Primary Generalized Tonic-Clonic (PGTC) seizures

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