Diabetes Mellitus, Type 2 Clinical Trials
A listing of Diabetes Mellitus, Type 2 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 25 clinical trials
UPENN Case Test Trial 1 In Different Account (Do Not Make Any Change)
UPENN Case Test Trial 1 In Different Account (Do Not Make Any Changes)
“The Shift Worker’s Microbiome”
We are looking for healthy males, age 40-59 years old, non-smoking un-medicated who work the "shift-work" schedule (>3 shifts per month outside 7 am-6 pm for the past 10 or more years & own a smartphone which installs the remote sensing applications. or "day workers" who work 7 am-6 pm …
Research Study for women with PCOS (Polycystic ovary syndrome)
Healthy women ages 18-45 with Polycystic Ovary Syndrome (PCOS) are invited to screen for a study participation in an investigational drug study
Normal Donor Human Bone Marrow Donation for Research
We are looking for healthy volunteers to donate bone marrow for research purposes. The Stem Cell & Xenograft Core provides bone marrow to laboratories on Penn’s campus researching leukemia and other blood disorders
Cardiovascular Inflammation Reduction Trial (CIRT): A randomized double-blind placebo controlled event-driven trial of weekly low-dose methotrexate (LDM) in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with type 2 diabetes or metabolic syndrome
This is an event-driven, multi-center, randomized, double-blind, placebo-controlled trial to determine whether methotrexate reduces heart attacks, strokes, or death in people who have already had at least one heart attack and have type 2 diabetes or metabolic syndrome. Metabolic syndrome is defined as a combination of problems including a large …
Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging
Randomized, single blinded crossover trial testing optimal interventions to adequately suppress myocardial glucose suppression. We will enroll up to 50 subjects in order to reach our target of 40 fully evaluable; 20 healthy volunteers and 20 patients with Type 2 diabetes mellitus. We will test whether dietary modification (ketogenic diet) …
Investigation of the Effect of Branched Chain Amino Acids on Fat-Induced Insulin Resistance in Healthy Adults.
Elevations in plasma levels of branched chain amino acids (BCAAs, comprising leucine, valine, and isoleucine), a large component of protein, are strongly associated with insulin resistance and type 2 diabetes, but mechanisms for this relationship are unclear. This protocol will determine whether excess BCAAs worsen free fatty acid-induced insulin resistance. …
Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized open-label cross-over trial
Diabetes is a major co-morbidity in pancreatic insufficient cystic fibrosis (PI-CF) and associated with worse outcomes. While reduced -cell mass contributes to the insulin secretory defects that characterizes cystic fibrosis-related diabetes (CFRD), other modifiable determinants appear operative in the emergence and progression of abnormal glucose tolerance towards diabetes. Identifying interventions …
