Diabetic Retinopathy Clinical Trials

IMProving Executive function Study (IMPRES)

Dr. Neill Epperson and her study team at the Penn Center for Women's Behavioral Wellness are seeking women to help understand the effects of a stimulant medication on memory and attention in women who underwent surgically induced menopause.

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A study that tests BI 1467335 in patients with diabetic eye disease (diabetic retinopathy). It looks at the way BI 1467335 is taken up the effects it has and how well it is tolerated.

A study that tests BI 1467335 in patients with diabetic eye disease (diabetic retinopathy). It looks at the way BI 1467335 is taken up, the effects it has, and how well it is tolerated.

The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addiction

We will examine differences in nAChR availability based on individual differences in the nicotine metabolism rate. Work conducted by Dr. Lermans group at Penn, in collaboration with Drs. Rachel Tyndale (University of Toronto) and Neal Benowitz (University of California, San Francisco) has documented differences in smoking cessation and treatment response …

Software to Measure Consumer Preferences in the Treatment of Depression

The purpose of the study is to develop a new web-based software program to evaluate consumer preferences in the treatment of depression and, potentially, other disorders. We will also assess the stability of preference scores in this study.

Targeting the Cholinergic Pathway in HIV-associated Inflammation and Cognitive Dysfunction

The primary outcomes are monocyte/macrophage and T-cell activation (CD16, CD163, and CCR2 expression; plasma CCL2 [MCP-1], sCD14; CD38/HLA-DR on CD8 cells) and neurocognitive performance (processing speed, verbal learning/memory, executive function). Exploratory outcomes include monocyte gene expression patterns and broad plasma cytokine analysis.