Chemotherapy Clinical Trials
A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 43 clinical trials
UPCC 44419: Randomized Trial of Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia (AML)
Patients will also receive standard chemotherapy of daunorubicin and cytarabine during induction and high-dose cytarabine during consolidation.
- 0 views
- 19 Feb, 2024
- 1 location
A single-arm open-label phase 2 study evaluating the efficacy and safety of abemaciclib in patients with recurrent oligodendroglioma
The study will be stratified by number of lines of prior alkylating chemotherapy (one prior line versus two or more prior lines). Eligibility criteria are such that of the 10 total subjects enrolled, at least 2 must have had only one prior line of alkylating chemotherapy.
- 0 views
- 19 Feb, 2024
- 1 location
Phase 1 Study of Autologous Anti-CD22 Chimeric Antigen Receptor Redirected T Cells (CART22-65s) alone and when co-administered with humanized Anti-CD19 Chimeric Antigen Receptor Redirected T cells (huCART19) In Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia
This is a single center, single arm, open-label Phase 1 study with two cohorts to determine the safety and feasibility of infusing CART22-65s with or without huCART19 after administration of lymphodepleting chemotherapy in adult patients with relapsed or refractory B-ALL.
- 0 views
- 19 Feb, 2024
- 1 location
A Phase I/II Study of Ixazomib and Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma
The purpose of this study is to see whether the addition of ixazomib to ibrutinib chemotherapy is effective in treating people who have relapsed or refractory mantle cell lymphoma and to examine the side effects associated with ixazomib in combination with ibrutinib.
- 0 views
- 19 Feb, 2024
- 1 location
UPCC 57418: A Phase III Multicenter Randomized Open Label Study of APR-246 in Combination with Azacitidine Versus Azacitidine Alone for the Treatment of TP53 Mutant Myelodysplastic Syndromes
This is a study of the effectiveness and safety of giving the experimental drug, APR-246, together with the drug azacitidine to patients with MDS that has not yet been treated with chemotherapy or hypomethylating agents like azacitidine, compared with just giving azacitidine alone.
- 0 views
- 19 Feb, 2024
- 1 location
A Phase III Randomized Placebo-Controlled Study to Examine the Efficacy and Safety of DAS181 for the Treatment of Lower Respiratory Tract Parainfluenza Infection in Immunocompromised Subjects
Key eligibility criteria are being diagnosed with PIV having received a solid organ or stem cell transplant at any time in the past, or past history of being treated with chemotherapy for solid tumor or blood-related malignancy. The main study intervention is treatment with study drug or placebo for 7-10 …
- 0 views
- 19 Feb, 2024
- 1 location
Cardiovascular function in leukemia patients: an observational prospective study
All patients will be studied using echocardiograms and blood tests before chemotherapy, 14 days, 28 days, 45-60 days, 6 months, and 12 months after the first dose of chemotherapy, for a total of 6 studies in 1 year.
- 0 views
- 19 Feb, 2024
- 1 location
Substrate targeted ablation using the Cool Flex catheter ablation system for the reduction of Ventricular Tachycardia
The purpose of the study is to compare the effectiveness of the Cool Flex Irrigated Catheter Ablation System to routine drug therapy without ablation to treat VT or prevent VT from developing in patients at risk. The study will also evaluate the safety of the catheter device.
- 0 views
- 19 Feb, 2024
- 1 location
A Phase 2/3 Randomized Open-Label Study of Toca 511 a Retroviral Replicating Vector Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma
This is a multicenter, randomized, open-label study of Toca 511 and Toca FC versus standard of care (SOC) that comprises Investigators choice of either single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects undergoing resection for first or second recurrence (including this recurrence) of glioblastoma or anaplastic astrocytoma.
- 0 views
- 19 Feb, 2024
- 1 location
SIMCAP (Surgery in Metastatic Carcinoma of Prostate): Phase 2.5 multi-institution randomized prospective clinical trial evaluating the impact of cytoreductive radical prostatectomy combined with best systemic therapy on oncologic and quality of life outcomes in men with newly diagnosed metastatic prostate cancer
CRP removes as much of the cancer as possible (and radical prostatectomy removes only prostate) while BST uses drugs toxic to cancer cells: chemotherapy and androgen deprivation therapy (ADT: decreases hormones necessary for cancer growth). However, BST eventually stops working.
- 0 views
- 19 Feb, 2024
- 1 location