Gliomas Clinical Trials
A listing of Gliomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 5 clinical trials
A phase II open-label study of ONC201 in adults with recurrent high-grade glioma
This is A phase II, open-label study of ONC201 in adults with recurrent high- grade glioma. Subjects will be age 18 or older with a histone H3 K27M mutant glioma that has progressed after radiation therapy. The primary objective is to estimate the overall response rate (ORR) of ONC201 in …
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- 19 Feb, 2024
- 1 location
A biospecimen collection study to evaluate the pharmacokinetic pharmacodynamic and resistance profile to trametinib and dabrafenib in BRAF-V600E mutated recurrent gliomas
The outlined research study is not of therapeutic intent, involving only the collection of blood, cerebrospinal fluid, and tissue samples to evaluate pharmacokinetics and resistance.
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- 19 Feb, 2024
- 1 location
A Study to Evaluate the Safety and Feasibility of Exablate Model 4000 Type-2 to temporarily mediate Blood-Brain Barrier Disruption (BBBD) in patients with suspected infiltrating glioma in the setting of planned surgical interventions
The goal of this prospective, non-randomized, single-arm study is to evaluate the safety and feasibility of using ExAblate Model 4000 Type-2 Neuro-System as a tool to disrupt the blood brain barrier in a temporary and localized fashion in patients with suspected infiltrating glioma undergoing planned surgical interventions.
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- 19 Feb, 2024
- 1 location
