Muscular Dystrophy Clinical Trials

A listing of Muscular Dystrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 79 clinical trials
Open-Labeled Trial Of Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Heart Transplants From Hepatitis C-Positive Donors

Since 2006, there has been a 50% increase in the number of adults added to the heart transplant waitlist in the US. Yet the persistent organ donor shortage has led to only a 25% increase in the number of transplants, and a 25% increase in the number of patients removed …

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  • 19 Feb, 2024
  • 1 location
Prevention of Mortality with Long-Term Administration of Human Albumin in Subjects with Decompensated Cirrhosis and Ascites

This study is designed to evaluate the effects of Albutein 20% infusion on long-term survival (1-year transplant-free) in liver cirrhosis compared to the Standard Medical Treatment (SMT).

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  • 19 Feb, 2024
  • 1 location
Optimization of Clinical Trial Design in Cutaneous Lupus

In the past, clinical trials on cutaneous lupus erythematosus (CLE) have not used patient-reported outcome measures to evaluate treatment efficacy; however, recent studies with small numbers of patients with CLE have compared questionnaires before and after treatment. Overall, there is little data available on changes in patient-reported outcome measures in …

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  • 19 Feb, 2024
  • 1 location
A Phase 2B Randomized Double-Blind Placebo-Controlled Study Evaluating the Safety and Efficacy of BMS-986036 (PEG-FGF21) in Adults with Nonalcoholic Steatohepatitis (NASH) and Compensated Liver Cirrhosis

A phase 2B, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of BMS-986036 in subjects with NASH and compensated cirrhosis. The treatment period is 48 weeks, with drug administered as a once-weekly injection. There is also a follow-up period to assess long-term bone mineral density and immunogenicity. Target population …

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  • 19 Feb, 2024
  • 1 location
A Phase 1 Randomized Placebo-Controlled Blinded Multiple Ascending Dose Study to Evaluate VIB7734 in Systemic Lupus Erythematosus Cutaneous Lupus Erythematosus Sjogrens Syndrome Systemic Sclerosis Polymyositis and Dermatomyositis

A Phase 1, randomized, blinded,placebo-controlled study to evaluate the safety and tolerability of multiple-ascending SC doses of VIB7734 in selected autoimmune diseases (SLE, CLE, Sjogrens syndrome, systemic sclerosis, polymyositis, dermatomyositis), and efficacy on skin lupus activity. 32 subjects will be enrolled in 3 cohorts. Cohort 1 has been completed. 24 …

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  • 19 Feb, 2024
  • 1 location
A Phase 3 Randomized Comparator-Controlled Clinical Trial to Study the Efficacy of Pembrolizumab (MK-3475) in Combination with Bacillus Calmette-Guerin (BCG) in Participants with High Risk Non-muscle Invasive Bladder Cancer (NMIBC) that is Persistent or Recurrent Following BCG Induction (KEYNOTE-676)

This study will involve patients with high risk non-muscle invasive bladder cancer (NMIBC) that is persistent (cancer stays) or recurrent (cancer comes back) following Bacillus Calmette-Guérin BCG treatment. The purpose of this study is to: o Test the safety of the study drugs, pembrolizumab in combination with Bacillus Calmette-Guerin (BCG) …

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  • 19 Feb, 2024
  • 1 location
A first in human phase 1 study in healthy volunteers and heterozygous carriers of a loss-of-function Granulin mutation causative of frontotemporal dementia to assess AL001 safety tolerability pharmacokinetics and pharmacodynamics

Please see section 1 of protocol

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  • 19 Feb, 2024
  • 1 location
A Phase 2 Multicenter Open-Label Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of AL001 in Heterozygous Carriers of Granulin or C9orf72 Mutations Causative of Frontotemporal Dementia

Please see section 1 of protocol

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  • 19 Feb, 2024
  • 1 location
A Pilot Study of Diffusion Weighted MRI to Assess Esophageal Tumor Response to Neoadjuvant Chemoradiation

The purpose of this study is to determine if a particular Magnetic Resonance Imaging (MRI) called Diffusion Weighted (dwMRI)) will detect changes in your tumor before and during treatment with chemotherapy and radiation for esophageal cancer. We used the dwMRI because it has been used in other types of cancers …

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  • 19 Feb, 2024
  • 1 location
A Phase 3 Double-Blind Randomized Placebo-Controlled Multicenter Study to Evaluate the Efficacy and Safety of Obeticholic Acid in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis

A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Obeticholic Acid in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis

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  • 19 Feb, 2024
  • 1 location