Vascular Diseases Clinical Trials
A listing of Vascular Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 8 clinical trials
A Trial of Crizanlizumab for the Treatment of Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL)
Retinal vasculopathy with cerebral leukoencephalopathy (RVCL) is a very rare and fatal genetic condition that affects the smallest blood vessels, especially of the brain and eye. It causes damage in the brain and eye, and there is currently no treatment to reduce these areas of damage. Crizanlizumab has been shown …
A Phase II Randomized Double-Blind Multicenter Multinational Placebo-Controlled Parallel-Groups Study to Evaluate the Safety and Efficacy of Intramuscular Injections of Allogeneic PLX-PAD Cells for the Treatment of Subjects with Intermittent Claudication (IC)
In this research study an investigational product called PLX-PAD will be tested to see if it helps claudication. PLX-PAD is made up of mesenchymal-like stromal cells (MSCs), which are similar to stem cells. These cells come from a human placenta (afterbirth) from chosen female donor volunteers. From animal experiments it …
A Phase 2 Multi-center Randomized Double-Blind Placebo-Controlled Dose Range Finding Study to Evaluate the Safety Hemodynamic Effects and Efficacy of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects who have Diabetic Foot Ulcer with Peripheral Arterial Disease
This is a Phase 2, randomized, double-blind, placebo-controlled, dose range finding study in subjects who have DFU with PAD. The study will enroll approximately 24 subjects. Two dose levels of PDA-002 (3 x 106 and 30 x 106 cells) versus placebo will be evaluated in 1:1:1 randomization approach. Subjects will …
Epidemiological study to characterize the prevalence and distribution of lipoprotein (a) levels among patients with established cardiovascular disease.
The purpose of this study is to collect information about the blood level of a specific marker (lipoprotein (a)). Similar to other blood lipids, such as the "bad cholesterol", lipoprotein (a) levels were found to be associated with the risk of hardening of the arteries, known as atherosclerosis, which leads …
Medtronic Evaluation of Multi-Electrode Phased RF Technology in Persistent Atrial Fibrillation
The study is expected to be conducted at approximately 40 centers located in Europe, Canada and the United States to support US Food and Drug Administration (FDA) marketing application. A maximum of 350 subjects will be enrolled in the study to ensure 300 subjects can be evaluated for the primary …
