Lung Disease Clinical Trials
A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 42 clinical trials
Open-Labeled Trial Of Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Lung Transplants From Hepatitis C-Positive Donors
There has only been a modest increase in the number of lung transplants each year, increasing from a yearly average of 2,400 between 2009 and 2011, to 2,800 in 2016. Despite this, more than 300 patients died or became too sick to transplant on the lung transplant waiting list in …
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- 19 Feb, 2024
- 1 location
Intraoperative molecular imaging of pulmonary nodules by BY SGM-101
Normal 0 false false false EN-US X-NONE X-NONE The research study is being conducted to determine if a new type of contrast agent can detect your cancer cells and to determine if the cancer has spread. The dye is unique for the following reasons: · It is not radioactive · …
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- 19 Feb, 2024
- 1 location
Pilot study for functional and structural MR Imaging of Endobroncial valve recipients using hyperpoloarized XENON-129
Once inhaled, this gas can provide information regarding lung structure and functionality, while also providing information regarding the changes that occur in the lung from EBV therapy and the efficacy of the therapy for treating COPD.
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- 19 Feb, 2024
- 1 location
A Phase 1/2 Randomized Double-Blind Placebo-Controlled Combined Single and Multiple Ascending Dose Study Evaluating the Safety Tolerability and Biological Activity of MRT5005 (COhCFTR mRNA/ICE LNP) Administered by Nebulization to Adult Subjects with Cystic Fibrosis
This research study is being done to study a new way to possibly treat cystic fibrosis lung disease. The investigational drug to be tested in the present study is known by its code name MRT5005. MRT5005 consists of very small particles containing messenger ribonucleic acid (mRNA), which has the genetic …
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- 19 Feb, 2024
- 1 location
Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
The purpose of this study is to find if adding the study drug, nivolumab (also known as OPVIDO), will limit lung cancer from growing back in patients with early stage non-small cell lung cancer. Nivolumab is a drug that may turn on the body's immune system to attack any cancer …
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- 19 Feb, 2024
- 1 location
Intratumoral Gene Mediated Cytotoxic Immunotherapy (GMCI) For Resectable Non-Small Cell Lung Cancer
Surgery is the best treatment for patients with Stage I or II lung cancer; however, nearly 60% of patients have recurrence. Additional immunotherapeutic agents given before surgery may be greatly reduce recurrence.
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- 19 Feb, 2024
- 1 location
PERSPIRE: Preventing rehospitalization in lung transplant recipients through mHealth utilizing individualized rehabilitation prescriptions
Lung transplant recipients have the highest risk of readmission after the index admission among solid organ transplant patients. We hypothesize that targeted, individualized rehabilitation plans will reduce the risk of unplanned readmission in the first year after lung transplantation.To address this hypothesis, we will conduct a prospective cohort study of …
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- 19 Feb, 2024
- 1 location
Assessment of Chronic Lung Allograft Dysfunction Using Single-Breath & Multi-Breath Hyperpolarized Xenon 129 MRI
The research study is being conducted to determine the effectiveness of using hyperpolarized xenon-129 (HP 129-Xe) magnetic resonance imaging (MRI) in diagnosing and predicting the clinical course of patients who received lung transplantation.
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- 19 Feb, 2024
- 1 location
Study Evaluating the Safety and Efficacy of Itacitinib in Participants With Bronchiolitis Obliterans Syndrome Following Lung Transplantation
Normal 0 false false false EN-US X-NONE X-NONE You are being invited to participate in a research study because you have Bronchiolitis Obliterans Syndrome. Bronchiolitis Obliterans Syndrome (BOS) is a long term (chronic) rejection process that can occur in the transplanted lungs. Itacitinib works by blocking your body from producing …
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- 19 Feb, 2024
- 1 location
UPCC 09517: Phase II study of Pembrolizumab and Itacitinib (INCB039110) for First Line Treatment of Metastatic Non-Small Cell Lung Cancer Expressing PD-L1
The main purpose of this study is to examine the efficacy of adding itacitinib (also known as INCB039110) to pembrolizumab in patients with previously untreated metastatic non-small cell lung cancer.
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- 19 Feb, 2024
- 1 location