Smoking Cessation Clinical Trials

RISE (Research in Smoking Elimination)

The main purpose of this research study is to assess how quitting smoking affects memory and attention.

Testing Novel Pharmacogenetic and Adherence Optimization Treatments to Improve the Effectiveness of Smoking Cessation Treatments for Smokers with HIV

The research study is being conducted to examine the effects of personalized smoking cessation medication treatment in order to help people with HIV/AIDS to quit smoking. During the study, participants will take either varenicline (brand name Chantix®) or use the nicotine patch, and they will receive smoking cessation therapy with …

Daily Liraglutide for Nicotine Dependence

Liraglutide is approved by the FDA for chronic weight management when combined with a reduced-calorie meal plan and physical activity. The use of liraglutide for smoking cessation in this study is investigational. Liraglutide comes in a pre-filled pen and is self-injected one time per day into the abdomen, thigh, or …

The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addiction

Rachel Tyndale (University of Toronto) and Neal Benowitz (University of California, San Francisco) has documented differences in smoking cessation and treatment response between slow and normal metabolizers of nicotine. Nicotine is metabolized primarily by the CYP2A6 enzyme to the inactive metabolites cotinine and 3-hydroxycotinine.

Pragmatic Clinical Trial Comparing Smoking Cessation Interventions among Underserved Patients who are referred for Lung Cancer Screening

Correspondingly, they may stand to preferentially benefit from smoking cessation interventions delivered in conjunction with LDCT. However, it is unknown which interventions best promote cessation in the screening context.

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