Insomnia Clinical Trials

Telemedicine vs in-person delivery of cognitive behavioral treatment of insomnia: a mixed methods analysis

Cognitive behavioral therapy for insomnia (CBT-I) has been the gold standard for the treatment of insomnia. There is a need to increase access to treatment, particularly for patients in more rural locations where providers may be scarce.

Chronic insomnia and CSF markers of dementia

The purpose of this study is to identify the relationship between chronic sleep disturbance and chemicals in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.

Chronic insomnia and CSF markers of dementia - Phase 2

Longitudinal studies have found that sleep disturbance often precedes and increases risk for dementia by several years.The purpose of this study is to examine the relationship between chronic insomnia and dementia biomarkers and orexin levels found in cerebrospinal fluid (CSF). Fifteen adults age 30-50 with chronic insomnia will undergo overnight …

Three Approaches to Maintenance Therapy for Chronic Insomnia in Older Adults (R01AG054521)

Medication is FDA approved. The present study is a further evaluation of the behavioral pharmacotherapeutic strategy (i.e., partial reinforcement following the obtention of treatment response with standard treatment) with a particular focus on 1) how low a dose may be used (dose = frequency of active medication) and 2) how …

Test Trial: Penn Insomnia Study

this is a test study. test test test

TapToSleep: Guided Behavioral Approaches for Insomnia in Older Adults

The University of Pennsylvania, in partnership with Advanced Medical Electronics, have developed a low-risk, non-pharmacologic intervention that can be implemented on mobile devices for the treatment of insomnia. The purpose of this study is to examine the effects of this smartphone-delivered behavioral treatment for insomnia in older adults.

Effects of Insomnia Treatment on Metabolism in Patients with Depression

You may be eligible for one of our current research studies:Cognitive behavioral therapy for insomnia (CBT-I) has been the ‘gold standard’ for the treatment of insomnia. Insomnia and depression are highly related, and there’s a need for developing new treatments for depression.

Changing the Trajectory of Mild Cognitive Impairment with CPAP Treatment of Obstructive Sleep Apnea (Memories 2)

Are you having any trouble with your memory or sleep?This research study will explore whether treating sleep apnea can improve memory. Compensation is up to $300 for the participant's time and up to $100 for the study partner.

The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer Patients

The purpose of the current study is to assess the effectiveness of a behavioral treatment for insomnia (also known as Cognitive Behavioral Therapy for Insomnia) on both insomnia and cancer-related pre and post Radiation Therapy. Information from the primary study will be used in conjunction with the data from this …

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